IF (Immunofluorescence)
(Immunofluorescent analysis of 293 cells using AAA118990 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Rabbit anti-Human, Mouse HM13 Polyclonal Antibody | anti-HM13 antibody
HM13 Antibody
Gene Names
HM13; H13; SPP; IMP1; PSL3; IMPAS; SPPL1; PSENL3; IMPAS-1; MSTP086
Reactivity
Human, Mouse
Applications
Immunofluorescence, Western Blot, ELISA
Purity
>95%, Protein G Purified
Synonyms
HM13, Antibody; HM13 Antibody; Minor histocompatibility antigen H13 (EC:3.4.23.-); HM13; H13; IMP1; PSL3; SPP; MSTP086; Intramembrane protease 1; IMP-1; IMPAS-1; hIMP1; Presenilin-like protein 3; Signal peptide peptidase; anti-HM13 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
377
Applicable Applications for anti-HM13 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Minor histocompatibility antigen H13 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34950 / sc-34949
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IF (Immunofluorescence)
(Immunofluorescent analysis of 293 cells using AAA118990 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
IF (Immunofluorescence)
(Immunofluorescent analysis of 293 cells using AAA118990 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
WB (Western Blot)
(Western blotAll lanes: HM13 antibody at 6ug/ml+ Mouse liver tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 42,47,44,37 kDaObserved band size: 41 kDa)
WB (Western Blot)
(Western blotAll lanes: HM13 antibody at 6ug/ml+ Mouse liver tissueGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 42,47,44,37 kDaObserved band size: 41 kDa)
Related Product Information for anti-HM13 antibody
Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides (PubMed:11714810). May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein (PubMed:12145199). Involved in the intramembrane cleavage of the integral membrane protein PSEN1 (PubMed:12077416, PubMed:11714810, PubMed:14741365). Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139-dependent manner (PubMed:25239945). May play a role in graft rejection (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,814 Da
NCBI Official Full Name
minor histocompatibility antigen H13 isoform 1
NCBI Official Synonym Full Names
histocompatibility (minor) 13
NCBI Official Symbol
HM13
NCBI Official Synonym Symbols
H13; SPP; IMP1; PSL3; IMPAS; SPPL1; PSENL3; IMPAS-1; MSTP086
NCBI Protein Information
minor histocompatibility antigen H13
UniProt Protein Name
Minor histocompatibility antigen H13
UniProt Gene Name
HM13
UniProt Synonym Gene Names
H13; IMP1; PSL3; SPP; IMP-1; IMPAS-1; hIMP1
UniProt Entry Name
HM13_HUMAN
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Product Notes
The HM13 hm13 (Catalog #AAA118990) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HM13 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's HM13 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the HM13 hm13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HM13, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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