Rabbit anti-Human HNRNPM Polyclonal Antibody | anti-HNRNPM antibody
HNRNPM Antibody (N-term)
IHC (Immunohiostchemistry)
(HNRNPM Antibody (N-term) (AAA287788)immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HNRNPM Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(HNRNPM Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the HNRNPM antibody detected the HNRNPM protein (arrow).)
expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The
hnRNPs are RNA binding proteins and they complex with heterogeneous
nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs
in the nucleus and appear to influence pre-mRNA processing and
other aspects of mRNA metabolism and transport. While all of the
hnRNPs are present in the nucleus, some seem to shuttle between the
nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic
acid binding properties. The protein encoded by this gene has three
repeats of quasi-RRM domains that bind to RNAs. This protein also
constitutes a monomer of the N-acetylglucosamine-specific receptor
which is postulated to trigger selective recycling of immature
GlcNAc-bearing thyroglobulin molecules. Multiple alternatively
spliced transcript variants are known for this gene but only two
transcripts has been isolated.
Marko, M., et al. Exp. Cell Res. 316(3):390-400(2010)
Russo, A., et al. Biochim. Biophys. Acta 1779(12):820-829(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Huang, X., et al. Sci. China, C, Life Sci. 43(6):648-654(2000)
NCBI and Uniprot Product Information
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Product Notes
The HNRNPM hnrnpm (Catalog #AAA287788) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 21-50. The HNRNPM Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HNRNPM can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the HNRNPM hnrnpm for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HNRNPM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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