IHC (Immunohiostchemistry)
(HRC Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HRC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human HRC Polyclonal Antibody | anti-HRC antibody
HRC Antibody (Center)
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
HRC, Antibody; HRC Antibody (Center); Sarcoplasmic reticulum histidine-rich calcium-binding protein; HRC; HCP; anti-HRC antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This HRC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the Central region of human HRC.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
277-306
Sequence Length
699
Applicable Applications for anti-HRC antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(HRC Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HRC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(HRC Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HRC Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(HRC Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the HRC antibody detected the HRC protein (arrow).)
WB (Western Blot)
(HRC Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the HRC antibody detected the HRC protein (arrow).)
Related Product Information for anti-HRC antibody
This gene encodes a luminal sarcoplasmic reticulum protein
identified by its ability to bind low-density lipoprotein with high
affinity. The protein interacts with the cytoplasmic domain of
triadin, the main transmembrane protein of the junctional
sarcoplasmic reticulum (SR) of skeletal muscle. The protein
functions in the regulation of releasable calcium into the SR.
identified by its ability to bind low-density lipoprotein with high
affinity. The protein interacts with the cytoplasmic domain of
triadin, the main transmembrane protein of the junctional
sarcoplasmic reticulum (SR) of skeletal muscle. The protein
functions in the regulation of releasable calcium into the SR.
References
Arvanitis, D.A., et al. Eur. Heart J. 29(20):2514-2525(2008)
Arvanitis, D.A., et al. Am. J. Physiol. Heart Circ. Physiol. 293 (3), H1581-H1589 (2007) :
Fan, G.C., et al. Am. J. Physiol. Heart Circ. Physiol. 287 (4), H1705-H1711 (2004) :
Anderson, J.P., et al. Mol. Cell. Biol. 24(9):3757-3768(2004)
Adkins, J.N., et al. Mol. Cell Proteomics 1(12):947-955(2002)
Arvanitis, D.A., et al. Am. J. Physiol. Heart Circ. Physiol. 293 (3), H1581-H1589 (2007) :
Fan, G.C., et al. Am. J. Physiol. Heart Circ. Physiol. 287 (4), H1705-H1711 (2004) :
Anderson, J.P., et al. Mol. Cell. Biol. 24(9):3757-3768(2004)
Adkins, J.N., et al. Mol. Cell Proteomics 1(12):947-955(2002)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80244
NCBI Official Full Name
sarcoplasmic reticulum histidine-rich calcium-binding protein
NCBI Official Synonym Full Names
histidine rich calcium binding protein
NCBI Official Symbol
HRC
NCBI Protein Information
sarcoplasmic reticulum histidine-rich calcium-binding protein
UniProt Protein Name
Sarcoplasmic reticulum histidine-rich calcium-binding protein
UniProt Gene Name
HRC
UniProt Synonym Gene Names
HCP
UniProt Entry Name
SRCH_HUMAN
Similar Products
Product Notes
The HRC hrc (Catalog #AAA288892) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 277-306. The HRC Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HRC can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the HRC hrc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HRC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.