WB (Western Blot)
(Anti-Huntingtin antibody, AAA45669, All Western blottingAll lanes: Anti-HTT(AAA45669) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: U87 Whole Cell Lysate at 40ugPredicted bind size: 348KDObserved bind size: 348KD)
Rabbit Huntingtin Polyclonal Antibody | anti-HTT antibody
Anti-Huntingtin antibody
Gene Names
HTT; HD; IT15
Reactivity
Human; Predicted: Mouse, Rat
Applications
Western Blot
Purity
Immunogen affinity purified
Synonyms
Huntingtin, Antibody; Anti-Huntingtin antibody; Huntingtin; huntingtin; AI256365 antibody; C430023I11Rik antibody; HD antibody; HD protein antibody; HDH antibody; HTT antibody; Huntingtin antibody; HUNTINGTON CHOREA antibody; Huntington disease protein antibody; IT 15 antibody; IT15 antibody; OTTMUSP00000026909 antibody; ZHD antibody; anti-HTT antibody
Host
Rabbit
Reactivity
Human; Predicted: Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
No cross reactivity with other proteins.
Purity/Purification
Immunogen affinity purified
Form/Format
Lyophilized; Contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
Applicable Applications for anti-HTT antibody
WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human HTT (3106-3121aa ELDRRAFQSVLEVVAA), different from the related mouse and rat sequences by two amino acids.
Reconstitution
0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
WB (Western Blot)
(Anti-Huntingtin antibody, AAA45669, All Western blottingAll lanes: Anti-HTT(AAA45669) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: U87 Whole Cell Lysate at 40ugPredicted bind size: 348KDObserved bind size: 348KD)
WB (Western Blot)
(Anti-Huntingtin antibody, AAA45669, All Western blottingAll lanes: Anti-HTT(AAA45669) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: U87 Whole Cell Lysate at 40ugPredicted bind size: 348KDObserved bind size: 348KD)
Related Product Information for anti-HTT antibody
The huntingtin gene, also called HTT or HD(Huntington disease) gene, is the IT15("interesting transcript 15") gene which codes for a protein called the huntingtin protein. It is mapped to 4p16.3. The protein has no sequence homology with other proteins and is highly expressed in neurons and tests in humans and rodents. HTT upregulates the expression of Brain Derived Neurotrophic Factor(BDNF) at the transcription level, and this gene is required for normal development. The HTT protein is involved in vesicle trafficking as it interacts with HIP1, a clathrin-binding protein, to mediate endocytosis, the absorption of materials into a cell. HTT was also visualized as punctate staining likely to represent nerve endings. What's more, wildtype HTT may function in the nucleus in the assembly of nuclear matrix-bound protein complexes involved with transcriptional repression and RNA processing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Huntingtin
NCBI Official Synonym Full Names
huntingtin
NCBI Official Symbol
HTT
NCBI Official Synonym Symbols
HD; IT15
NCBI Protein Information
huntingtin; huntington disease protein
UniProt Protein Name
Huntingtin
UniProt Gene Name
HTT
UniProt Synonym Gene Names
HD; IT15; HD protein
UniProt Entry Name
HD_HUMAN
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Product Notes
The HTT htt (Catalog #AAA45669) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Huntingtin antibody reacts with Human; Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Huntingtin can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the HTT htt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Huntingtin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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