Rabbit HUS1 Polyclonal Antibody | anti-HUS1 antibody

HUS1 Polyclonal Antibody

Cat. Num. AAA312889

• Gene Names: HUS1; hHUS1
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot
• Purity: Affinity purification
• Synonyms: HUS1, Antibody; HUS1 Polyclonal Antibody; HUS1; hHUS1; anti-HUS1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity purification
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH7.4, 150mM NaCl, 0.02% sodium azide and 76% glycerol.; PBS with 0.02% sodium azide, 50% glycerol, pH7.29
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-HUS1 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Recombinant fusion protein of human HUS1 (NP_004498.1)
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human uterine cancer using HUS1 antibody at dilution of 1:100 .)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human gastric cancer using HUS1 antibody at dilution of 1:100 .)

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded rat heart using HUS1 antibody at dilution of 1:100 .)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded rat liver using HUS1 antibody at dilution of 1:100 .)

WB (Western Blot)

(Western blot analysis of extracts of mouse kidney, using HUS1 antibody at 1:1000 dilution.)

Related Product Information for anti-HUS1 antibody

The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.

Product Categories/Family for anti-HUS1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 4758576
• NCBI GeneID: 3364
• NCBI Accession #: NP_004498.1
• NCBI GenBank Nucleotide #: NM_004507.3
• UniProt Accession #: O60921; B4DFI9
• Molecular Weight: 29,287 Da
• NCBI Official Full Name: checkpoint protein HUS1
• NCBI Official Synonym Full Names: HUS1 checkpoint homolog (S. pombe)
• NCBI Official Symbol: HUS1
• NCBI Official Synonym Symbols: hHUS1
• NCBI Protein Information: checkpoint protein HUS1; hus1+-like protein
• UniProt Protein Name: Checkpoint protein HUS1
• UniProt Gene Name: HUS1
• UniProt Synonym Gene Names: hHUS1
• UniProt Entry Name: HUS1_HUMAN