IHC (Immunohiostchemistry)
(HYAL1 Antibody (C-term) (AAA284969)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HYAL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human HYAL1 Polyclonal Antibody | anti-HYAL1 antibody
HYAL1 Antibody (C-term)
Gene Names
HYAL1; MPS9; NAT6; LUCA1; HYAL-1
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
HYAL1, Antibody; HYAL1 Antibody (C-term); Hyaluronidase-1; Hyal-1; Hyaluronoglucosaminidase-1; Lung carcinoma protein 1; LuCa-1; HYAL1; LUCA1; anti-HYAL1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This HYAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human HYAL1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
280-309
Sequence Length
336
Applicable Applications for anti-HYAL1 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(HYAL1 Antibody (C-term) (AAA284969)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HYAL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(HYAL1 Antibody (C-term) (AAA284969)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HYAL1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(HYAL1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HYAL1 antibody detected the HYAL1 protein (arrow).)
WB (Western Blot)
(HYAL1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the HYAL1 antibody detected the HYAL1 protein (arrow).)
Related Product Information for anti-HYAL1 antibody
This gene encodes a lysosomal hyaluronidase.
Hyaluronidases intracellularly degrade hyaluronan, one of the major
glycosaminoglycans of the extracellular matrix. Hyaluronan is
thought to be involved in cell proliferation, migration and
differentiation. This enzyme is active at an acidic pH and is the
major hyaluronidase in plasma. Mutations in this gene are
associated with mucopolysaccharidosis type IX, or hyaluronidase
deficiency. The gene is one of several related genes in a region of
chromosome 3p21.3 associated with tumor suppression. Multiple
transcript variants encoding different isoforms have been found for
this gene.
Hyaluronidases intracellularly degrade hyaluronan, one of the major
glycosaminoglycans of the extracellular matrix. Hyaluronan is
thought to be involved in cell proliferation, migration and
differentiation. This enzyme is active at an acidic pH and is the
major hyaluronidase in plasma. Mutations in this gene are
associated with mucopolysaccharidosis type IX, or hyaluronidase
deficiency. The gene is one of several related genes in a region of
chromosome 3p21.3 associated with tumor suppression. Multiple
transcript variants encoding different isoforms have been found for
this gene.
Product Categories/Family for anti-HYAL1 antibody
References
Lanktree, M.B., et al. Blood 116(12):2160-2163(2010)
Gasingirwa, M.C., et al. Biochem. J. 430(2):305-313(2010)
Tzuman, Y.C., et al. Neoplasia 12(1):51-60(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Wang, X.Y., et al. Chin. Med. J. 122(11):1300-1304(2009)
Gasingirwa, M.C., et al. Biochem. J. 430(2):305-313(2010)
Tzuman, Y.C., et al. Neoplasia 12(1):51-60(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Wang, X.Y., et al. Chin. Med. J. 122(11):1300-1304(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
48368
NCBI Official Full Name
hyaluronidase-1 isoform 1
NCBI Official Synonym Full Names
hyaluronoglucosaminidase 1
NCBI Official Symbol
HYAL1
NCBI Official Synonym Symbols
MPS9; NAT6; LUCA1; HYAL-1
NCBI Protein Information
hyaluronidase-1
UniProt Protein Name
Hyaluronidase-1
UniProt Gene Name
HYAL1
UniProt Synonym Gene Names
LUCA1; Hyal-1; LuCa-1
UniProt Entry Name
HYAL1_HUMAN
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Product Notes
The HYAL1 hyal1 (Catalog #AAA284969) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 280-309. The HYAL1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HYAL1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the HYAL1 hyal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HYAL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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