IF (Immunofluorescence)
(IF of IgD on a FFPE Tosil Tissue)
Rabbit IgD Polyclonal Antibody | anti-IgD antibody
IgD/FITC, Rpab
Applications
Immunohistochemistry
Synonyms
IgD, Antibody; IgD/FITC, Rpab; anti-IgD antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Form/Format
Concentrate or Prediluted
Sequence Length
432
Applicable Applications for anti-IgD antibody
IHC (Immunohistochemistry)
Immunogen
IgD isolated from a pool of normal human plasma.
Localization
Cytoplasmic, Membranous
Control
Tonsil, Lymph Node
Preparation and Storage
Store at 2-8 degree C in the dark.
IF (Immunofluorescence)
(IF of IgD on a FFPE Tosil Tissue)
IF (Immunofluorescence)
(IF of IgD on a FFPE Tosil Tissue)
Dilution Info
Dilution Info
Related Product Information for anti-IgD antibody
IgD makes up about 1% of proteins in the plasma membranes of immature Blymphocytes (coexpressed with IgM) and is also found in serum in very small amounts. It is monomeric and incorporates the alpha-heavy chain in its structure. IgD’s function is currently unknown, as mice lacking IgD seem to retain normal immune responses (implying redundancy if not lack of function), and IgD ceases to be expressed in activated B-lymphocytes. It may function as a regulatory antigen receptor. IgD is the major antigen receptor isotype co-expressed with IgM on the surface of most peripheral B cells in mice and humans.
The IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived from Lymphomas, specifically Marginal Zone Lymphoma. Renal involvement in systemic lupus erythematosus (SLE) is associated with production of antibodies to double stranded DNA, deposition of immune complexes and organ damage. Lupus nephritis patients were characterized by increased percentage of immature/early-transitional Bcells (CD27-IgD+CD21-), higher frequency of activated switched memory (SM, CD27+IgD-CD21-) and exhausted memory B-cells (CD27-IgD-), and decrease in nonswitched memory (NSM, CD27+IgD+) B-cells.
The IgD antibody reacts with surface immunoglobulin IgD delta chains. This antibody is useful when identifying Leukemias, Plasmacytomas, and B-cell lineage derived from Lymphomas, specifically Marginal Zone Lymphoma. Renal involvement in systemic lupus erythematosus (SLE) is associated with production of antibodies to double stranded DNA, deposition of immune complexes and organ damage. Lupus nephritis patients were characterized by increased percentage of immature/early-transitional Bcells (CD27-IgD+CD21-), higher frequency of activated switched memory (SM, CD27+IgD-CD21-) and exhausted memory B-cells (CD27-IgD-), and decrease in nonswitched memory (NSM, CD27+IgD+) B-cells.
Product Categories/Family for anti-IgD antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
IgD immunoglobulin heavy chain constant region, partial
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Product Notes
The IgD (Catalog #AAA59326) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IgD can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the IgD for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IgD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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