IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using IGF2R (Phospho-Ser2409) antibody.)
Rabbit IGF2R (Phospho-Ser2409) Polyclonal Antibody | anti-IGF2R antibody
IGF2R (Phospho-Ser2409) Antibody
Gene Names
IGF2R; MPR1; MPRI; CD222; CIMPR; M6P-R
Reactivity
Human, mouse, rat
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
IGF2R (Phospho-Ser2409), Antibody; IGF2R (Phospho-Ser2409) Antibody; Cation-independent mannose-6-phosphate receptor; CI Man-6-P receptor; CI-MPR; M6PR; 300 kDa mannose 6-phosphate receptor; MPR 300; Insulin-like growth factor 2 receptor; Insulin-like growth factor II receptor; IGF-II receptor; M6P/IGF2 receptor; M6P/IGF2R; CD222; IGF2R; MPRI; anti-IGF2R antibody
Host
Rabbit
Reactivity
Human, mouse, rat
Clonality
Polyclonal
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
2,491
Applicable Applications for anti-IGF2R antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
synthetic peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using IGF2R (Phospho-Ser2409) antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue using IGF2R (Phospho-Ser2409) antibody.)
WB (Western Blot)
(Western blot analysis of extracts from COS-7 cells, treated with UV (15mins), using IGF2R (Phospho-Ser2409) antibody.)
WB (Western Blot)
(Western blot analysis of extracts from COS-7 cells, treated with UV (15mins), using IGF2R (Phospho-Ser2409) antibody.)
Related Product Information for anti-IGF2R antibody
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Product Categories/Family for anti-IGF2R antibody
References
Morgan D.O.,et al.Nature 329:301-307(1987).
Oshima A.,et al.J. Biol. Chem. 263:2553-2562(1988).
Gemma A.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Killian J.K.,et al.Mamm. Genome 10:74-77(1999).
Mungall A.J.,et al.Nature 425:805-811(2003).
Oshima A.,et al.J. Biol. Chem. 263:2553-2562(1988).
Gemma A.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Killian J.K.,et al.Mamm. Genome 10:74-77(1999).
Mungall A.J.,et al.Nature 425:805-811(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
274375
NCBI Official Full Name
cation-independent mannose-6-phosphate receptor
NCBI Official Synonym Full Names
insulin-like growth factor 2 receptor
NCBI Official Symbol
IGF2R
NCBI Official Synonym Symbols
MPR1; MPRI; CD222; CIMPR; M6P-R
NCBI Protein Information
cation-independent mannose-6-phosphate receptor
UniProt Protein Name
Cation-independent mannose-6-phosphate receptor
UniProt Gene Name
IGF2R
UniProt Synonym Gene Names
MPRI; CI Man-6-P receptor; CI-MPR; M6PR; MPR 300; IGF-II receptor; M6P/IGF2R
UniProt Entry Name
MPRI_HUMAN
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Product Notes
The IGF2R igf2r (Catalog #AAA285594) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IGF2R (Phospho-Ser2409) Antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's IGF2R (Phospho-Ser2409) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the IGF2R igf2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGF2R (Phospho-Ser2409), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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