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product-image-AAA289701_FCM11.jpg FCM/FACS (Flow Cytometry) (IGFALS Antibody (Center) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Rabbit anti-Human, mouse IGFALS Polyclonal Antibody | anti-IGFALS antibody

IGFALS Antibody (Center)

Gene Names
IGFALS; ALS; ACLSD
Reactivity
Human, mouse
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
IGFALS, Antibody; IGFALS Antibody (Center); Insulin-like growth factor-binding protein complex acid labile subunit; ALS; IGFALS; anti-IGFALS antibody
Ordering
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This IGFALS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the Central region of human IGFALS.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
308-335
Sequence Length
643
Applicable Applications for anti-IGFALS antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

FCM/FACS (Flow Cytometry)

(IGFALS Antibody (Center) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

product-image-AAA289701_FCM11.jpg FCM/FACS (Flow Cytometry) (IGFALS Antibody (Center) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

IHC (Immunohiostchemistry)

(Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with IGFALS Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

product-image-AAA289701_IHC13.jpg IHC (Immunohiostchemistry) (Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with IGFALS Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

WB (Western Blot)

(Western blot analysis of IGFALS Antibody (Center) in mouse spleen tissue, Jurkat cell line and mouse liver tissue lysates (35ug/lane). IGFALS (arrow) was detected using the purified Pab.)

product-image-AAA289701_WB15.jpg WB (Western Blot) (Western blot analysis of IGFALS Antibody (Center) in mouse spleen tissue, Jurkat cell line and mouse liver tissue lysates (35ug/lane). IGFALS (arrow) was detected using the purified Pab.)
Related Product Information for anti-IGFALS antibody
IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this protein are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.
Product Categories/Family for anti-IGFALS antibody
References
Leong S.R., Baxter R.C.Mol. Endocrinol. 6:870-876(1992)
Suwanichkul A.Endocrinology 141:833-838(2000)
Liu T., Qian W.-J.J. Proteome Res. 4:2070-2080(2005)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
66035
NCBI Official Full Name
insulin-like growth factor-binding protein complex acid labile subunit isoform 1
NCBI Official Synonym Full Names
insulin-like growth factor binding protein, acid labile subunit
NCBI Official Symbol
IGFALS
NCBI Official Synonym Symbols
ALS; ACLSD
NCBI Protein Information
insulin-like growth factor-binding protein complex acid labile subunit
UniProt Protein Name
Insulin-like growth factor-binding protein complex acid labile subunit
UniProt Gene Name
IGFALS
UniProt Synonym Gene Names
ALS; ALS
UniProt Entry Name
ALS_HUMAN

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Product Notes

The IGFALS igfals (Catalog #AAA289701) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 308-335. The IGFALS Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IGFALS can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the IGFALS igfals for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGFALS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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