Rabbit IL-16 Polyclonal Antibody | anti-IL16 antibody

IL-16 Antibody

Cat. Num. AAA40249

• Gene Names: IL16; LCF; NIL16; PRIL16; prIL-16
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: IL-16 Antibody is affinity chromatography purified via peptide column.
• Synonyms: IL-16, Antibody; IL-16 Antibody; IL-16; LCF; NIL16; PRIL16; prIL-16; Pro-interleukin-16; Lymphocyte chemoattractant factor; interleukin 16 (lymphocyte chemoattractant factor); anti-IL16 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This antibody will only detect the NIL-16 isoform.
• Purity/Purification: IL-16 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1332

• Applicable Applications for anti-IL16 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: IL-16 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human IL-16.
• Buffer: IL-16 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: IL-16 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of IL-16 in mouse brain tissue with IL-16 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of IL-16 in mouse brain tissue with IL-16 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of IL-16 in rat brain tissue lysate with IL-16 antibody at (A) 2.5 and (B) 5 μg/mL.)

Related Product Information for anti-IL16 antibody

IL-16 Antibody: IL-16 was initially identified as a chemotactic cytokine, but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases. The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4. Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders. At least two isoforms of IL-16 are known to exist; the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippocampus.

NCBI and Uniprot Product Information

• NCBI GI #: 36953836
• NCBI GeneID: 3603
• UniProt Accession #: Q14005; Q16435; Q6VVE6; Q6ZMQ7; Q9UP18; A6NM20; A8MU65; B5TY35; B9EGR6; H3BVH5
• Molecular Weight: 59,345 Da
• NCBI Official Full Name: neural interleukin 16 protein
• NCBI Official Synonym Full Names: interleukin 16
• NCBI Official Symbol: IL16
• NCBI Official Synonym Symbols: LCF; NIL16; PRIL16; prIL-16
• NCBI Protein Information: pro-interleukin-16; prointerleukin 16; neuronal interleukin 16; lymphocyte chemoattractant factor
• UniProt Protein Name: Pro-interleukin-16
• UniProt Gene Name: IL16
• UniProt Synonym Gene Names: IL-16; LCF
• UniProt Entry Name: IL16_HUMAN