Rabbit anti-Mouse IL-23 Polyclonal Antibody | anti-IL23A antibody

RABBIT ANTI HUMAN INTERLEUKIN-23 (N-TERMINAL)

Cat. Num. AAA49926

• Gene Names: IL23A; P19; SGRF; IL-23; IL-23A; IL23P19
• Reactivity: Mouse
• Applications: Western Blot
• Synonyms: IL-23, Antibody; RABBIT ANTI HUMAN INTERLEUKIN-23 (N-TERMINAL); anti-IL23A antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This item detects an epitope within the N-terminal (NT) domain of human interleukin-23 (IL-23), a 21kD heterodimeric cytokine structurally related to IL-12. IL-23 is composed of a p19 subunit encoded by the IL23A gene, and a p40 subunit of interleukin-12 (IL12B). IL-23 is expressed mainly by activated macrophages and dendritic cells, and plays an important role in bridging innate and adaptive responses. ; ; IL-23 activates a subset of T cells called Th17 cells, which are characterised by the production of interleukin-17. The IL-23/IL-17 pathway is essential for the induction and maintenance of brain and joint inflammatory autoimmune diseases, including Guillain Barre Syndrome, Multiple sclerosis and rheumatoid arthritis.
• Form/Format: Purified; Purified IgG - liquid
• Concentration: IgG concentration 1.0mg/ml (varies by lot)
• Sequence Length: 189

• Applicable Applications for anti-IL23A antibody: WB (Western Blot)
• Perservative Stabilisers: 0.02% Sodium Azide (NaN3)
• Immunogen: A 16 amino acid peptide from near the amino terminus of human IL-23.; Buffer Solution
• Antiserum Preparation: Antisera to human IL-23 (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
• Target Species: Human
• Preparation and Storage: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.; Shelf Life: 18 months from date of despatch.

Application Data

(Immunohistochemical staining of mouse pancreas With Rabbit anti Human interleukin-23 (AAA49926))

Application Data

(Western blot analysis of mouse pancreas lysate probed with Rabbit anti Human interleukin-23 (AAA49926) at 1(A) and 2(B) ug/ml)

Related Product Information for anti-IL23A antibody

MBS221463 detects an epitope within the N-terminal (NT) domain of human interleukin-23 (IL-23), a 21kD heterodimeric cytokine structurally related to IL-12. IL-23 is composed of a p19 subunit encoded by the IL23A gene, and a p40 subunit of interleukin-12 (IL12B). IL-23 is expressed mainly by activated macrophages and dendritic cells, and plays an important role in bridging innate and adaptive responses. IL-23 activates a subset of T cells called Th17 cells, which are characterised by the production of interleukin-17. The IL-23/IL-17 pathway is essential for the induction and maintenance of brain and joint inflammatory autoimmune diseases, including Guillain Barre Syndrome, Multiple sclerosis and rheumatoid arthritis.

NCBI and Uniprot Product Information

• NCBI GI #: 7706702
• NCBI GeneID: 51561
• NCBI Accession #: NP_057668.1
• NCBI GenBank Nucleotide #: NM_016584.2
• UniProt Accession #: Q9NPF7; Q6NZ80; Q6NZ82; Q9H2A5
• Molecular Weight: 20,730 Da
• NCBI Official Full Name: interleukin-23 subunit alpha
• NCBI Official Synonym Full Names: interleukin 23, alpha subunit p19
• NCBI Official Symbol: IL23A
• NCBI Official Synonym Symbols: P19; SGRF; IL-23; IL-23A; IL23P19
• NCBI Protein Information: interleukin-23 subunit alpha; IL-23 subunit alpha; IL-23-A; IL-23p19; JKA3 induced upon T-cell activation; interleukin 23 p19 subunit; interleukin-23 subunit p19; interleukin-six, G-CSF related factor
• UniProt Protein Name: Interleukin-23 subunit alpha
• UniProt Gene Name: IL23A
• UniProt Synonym Gene Names: SGRF; IL-23 subunit alpha; IL-23-A; IL-23p19
• UniProt Entry Name: IL23A_HUMAN