ICC (Immunocytochemistry)
(Immunocytochemistry of IL-27 in EL4 with IL-27 antibody at 10 μg/mL.)
Rabbit anti-Human, Mouse IL-27 Polyclonal Antibody | anti-IL27 antibody
IL-27 Antibody
Gene Names
IL27; p28; IL30; IL-27; IL27A; IL-27A; IL27p28
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
IL-27 Antibody is affinity chromatography purified via peptide column.
Synonyms
IL-27, Antibody; IL-27 Antibody; IL-27; p28; IL30; IL27A; IL-27A; IL27p28; Interleukin-27 subunit alpha; IL-27 subunit alpha; interleukin 27; anti-IL27 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
IL-27 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
243
Applicable Applications for anti-IL27 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
IL-27 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human IL-27.
Buffer
IL-27 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
IL-27 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of IL-27 in EL4 with IL-27 antibody at 10 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of IL-27 in EL4 with IL-27 antibody at 10 μg/mL.)
WB (Western Blot)
(Western blot analysis of IL-27 in A-20 cell lysate with IL-27 antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of IL-27 in A-20 cell lysate with IL-27 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-IL27 antibody
IL-27 Antibody: Like interleukin-23 (IL-23), IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the p40-related protein EBI3 and an IL-12 p35-related protein termed p28. IL-27 is produced after activation by antigen-presenting cells and induces proliferation of naïve but not memory CD4+ T-cells. It acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting the IL-27 is involved in the regulation of immune processes. It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,493 Da
NCBI Official Full Name
interleukin-27 subunit alpha
NCBI Official Synonym Full Names
interleukin 27
NCBI Official Symbol
IL27
NCBI Official Synonym Symbols
p28; IL30; IL-27; IL27A; IL-27A; IL27p28
NCBI Protein Information
interleukin-27 subunit alpha; IL27-A; IL-27-A; interleukin 30; interleukin-30; IL-27 p28 subunit; IL-27 subunit alpha
UniProt Protein Name
Interleukin-27 subunit alpha
UniProt Gene Name
IL27
UniProt Synonym Gene Names
IL27A; IL30; IL-27 subunit alpha; IL-27-A; IL27-A
UniProt Entry Name
IL27A_HUMAN
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Product Notes
The IL27 il27 (Catalog #AAA39885) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL-27 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IL-27 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the IL27 il27 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-27, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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