IHC (Immunohistochemisry)
(Immunohistochemical staining of paraffin-embedded PC3 xenograft using IL1RA antagonist antibody at a dilution of 1:500)
Rabbit IL1RA antagonist Polyclonal Antibody | anti-IL1RA antibody
IL1RA antagonist antibody
Gene Names
IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence
Purity
IL1RA antagonist antibody was purified by antigen-affinity chromatography
Synonyms
IL1RA antagonist, Antibody; IL1RA antagonist antibody; Polyclonal IL1RA antagonist; Anti-IL1RA antagonist; MGC10430; DIRA; ILRA-1; IL1RA; IL-1ra; ILRA 1; MVCD4; IL-1ra3; ICIL-1RA; IL1RN; IL1 inhibitor; IL1RN (IL1F3); IL-1RN; IL1F3; interleukin-1 receptor antagonist protein; IRAP; anti-IL1RA antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
IL1RA antagonist antibody was purified by antigen-affinity chromatography
Form/Format
Supplied as a concentrated soloution containing 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH 7.0). 0.01% Thimerosal was added as a preservative.
Concentration
1 mg/ml (varies by lot)
Sequence Length
177
Applicable Applications for anti-IL1RA antibody
WB (Western Blot), IHC (Immunohistochemistry), ICC (Immunocytochemistry), IF (Immunofluorescence)
Biological Significance
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha and interleukin 1, beta, and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.
Cross-Reactivity
Human
Immunogen
IL1RA antagonist antibody was raised in rabbit using a recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 127 of IL1 Receptor antagonist
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
IHC (Immunohistochemisry)
(Immunohistochemical staining of paraffin-embedded PC3 xenograft using IL1RA antagonist antibody at a dilution of 1:500)
IHC (Immunohistochemisry)
(Immunohistochemical staining of paraffin-embedded PC3 xenograft using IL1RA antagonist antibody at a dilution of 1:500)
WB (Western Blot)
(Western blot analysis of 30 ug whole cell lysate (A:MOLT4) using a 12 % SDS PAGE gel and IL1RA antagonist antibody at a dilution of 1:1000)
WB (Western Blot)
(Western blot analysis of 30 ug whole cell lysate (A:MOLT4) using a 12 % SDS PAGE gel and IL1RA antagonist antibody at a dilution of 1:1000)
IF (Immunofluorescence)
(Immunofluorescence analysis of methanol-fixed HeLa, using IL1ra antagonist antibody at 1:200 dilution.)
IF (Immunofluorescence)
(Immunofluorescence analysis of methanol-fixed HeLa, using IL1ra antagonist antibody at 1:200 dilution.)
Related Product Information for anti-IL1RA antibody
Affinity purified Rabbit polyclonal IL1RA antagonist antibody
Product Categories/Family for anti-IL1RA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20 kDa
NCBI Official Full Name
interleukin-1 receptor antagonist protein isoform 1
NCBI Official Synonym Full Names
interleukin 1 receptor antagonist
NCBI Official Symbol
IL1RN
NCBI Official Synonym Symbols
DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
NCBI Protein Information
interleukin-1 receptor antagonist protein
UniProt Protein Name
Interleukin-1 receptor antagonist protein
UniProt Gene Name
IL1RN
UniProt Synonym Gene Names
IL1F3; IL1RA; IL-1RN; IL-1ra; IRAP
UniProt Entry Name
IL1RA_HUMAN
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Product Notes
The IL1RA il1rn (Catalog #AAA107585) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IL1RA antagonist can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ICC (Immunocytochemistry), IF (Immunofluorescence). Researchers should empirically determine the suitability of the IL1RA il1rn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL1RA antagonist, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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