Rabbit IL1RA Polyclonal Antibody | anti-IL1RA antibody
IL1RA antibody
Gene Names
IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
Reactivity
Not determined
Applications
ELISA, Western Blot
Synonyms
IL1RA, Antibody; IL1RA antibody; Polyclonal IL1RA; Anti-IL1RA; ICIL-1RA; ILRA 1; IL-1Ra; IL-1R alpha; IL1RA; Interleukin 1R alpha; ILRA-1; IL-1RN; IRAP; anti-IL1RA antibody
Host
Rabbit
Reactivity
Not determined
Clonality
Polyclonal
Specificity
Human IL1RA
Form/Format
Sterile filtered lyophilized powder from PBS, pH 7.2. Centrifuge the vial prior to opening. Reconstitute in sterile water to a final concentration of 0.1-1.0mg/ml.
Concentration
50ug, lyophilized (varies by lot)
Sequence Length
143
Applicable Applications for anti-IL1RA antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Application Notes
ELISA: 0.5-2 ug/ml
Inhibition: 2.5-3.7 ug/ml
WB: 0.1-0.2 ug/ml
Inhibition: 2.5-3.7 ug/ml
WB: 0.1-0.2 ug/ml
Biological Significance
Interleukin-1 receptor antagonist (IL1RA) is a naturally occurring inflammatory inhibitor protein. It inhibits the activity of IL1a and IL1beta by competitively blocking binding to their type I and type II receptors. IL1Ra is produced by corneal epithelial cells, monocytes, neutrophils, macrophages, and fibroblasts. Therapeutically, IL1Ra may help in the treatment of sepsis, cachexia, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease.
Immunogen
E.coli derived recombinant Human IL-1RA
Preparation and Storage
Ships ambient or refrigerated. Upon receipt store at 4 degree C for shor term.; -20 degree C for long term. Avoid repeat freeze-thaw cycle.
Related Product Information for anti-IL1RA antibody
Affinity purified Rabbit polyclonal IL1RA antibody
Product Categories/Family for anti-IL1RA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17.2 kDa (predicted detection band MW)
NCBI Official Full Name
interleukin-1 receptor antagonist protein isoform 4
NCBI Official Synonym Full Names
interleukin 1 receptor antagonist
NCBI Official Symbol
IL1RN
NCBI Official Synonym Symbols
DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
NCBI Protein Information
interleukin-1 receptor antagonist protein
UniProt Protein Name
Interleukin-1 receptor antagonist protein
UniProt Gene Name
IL1RN
UniProt Synonym Gene Names
IL1F3; IL1RA; IL-1RN; IL-1ra; IRAP
UniProt Entry Name
IL1RA_HUMAN
Similar Products
Product Notes
The IL1RA il1rn (Catalog #AAA14336) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IL1RA antibody reacts with Not determined and may cross-react with other species as described in the data sheet. AAA Biotech's IL1RA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). ELISA: 0.5-2 ug/ml Inhibition: 2.5-3.7 ug/ml WB: 0.1-0.2 ug/ml. Researchers should empirically determine the suitability of the IL1RA il1rn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL1RA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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