WB (Western Blot)
(Western blot analysis of IL-36RN in 3T3 cell lysate with IL-36RN antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Mouse, Human IL36RN / IL1F5 Polyclonal Antibody | anti-IL36RN / IL1F5 antibody
Anti-IL36RN / IL1F5 Antibody (C-Terminus) IHC-plus
Gene Names
IL36RN; FIL1; FIL1D; IL1F5; IL1L1; PSORP; IL1HY1; IL1RP3; IL36RA; IL-36Ra; PSORS14; FIL1(DELTA)
Reactivity
Mouse, Human
Applications
ELISA, Western Blot, Immunofluorescence, Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
IL36RN / IL1F5, Antibody; Anti-IL36RN / IL1F5 Antibody (C-Terminus) IHC-plus; Rabbit Polyclonal (IgG) to Human IL36RN / IL1F5; Human IL36RN / IL1F5; FIL1; FIL1D; IL-1 delta; IL-1 related protein 3; IL-1HY1; IL-1RP3; IL-1-related protein 3; IL1RP3; IL1L1; IL36RA; Interleukin-1 delta; Family of interleukin 1-delta; FIL1 delta; IL-1L1; IL-1ra homolog 1; anti-IL36RN / IL1F5 antibody
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
IL-36RN antibody is human specific. At least two isoforms of IL-36RN are known to exist.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
155
Applicable Applications for anti-IL36RN / IL1F5 antibody
ELISA, WB (Western Blot), IF (Immunofluorescence), IHC (Immunohistochemistry)
Immunogen
IL36RN / IL1F5 antibody was raised against 19 amino acid peptide near the carboxy terminus of human IL-36RN.
Immunogen Description
19 amino acid peptide near the carboxy terminus of human IL-36RN.
Antigen Modification
C-Terminus
Target Species
Human
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
WB (Western Blot)
(Western blot analysis of IL-36RN in 3T3 cell lysate with IL-36RN antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of IL-36RN in 3T3 cell lysate with IL-36RN antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)
IF (Immunofluorescence)
(Immunofluorescence of IL-36RN in rat small intestine tissue with IL-36RN antibody at 20 ug/ml.)
IF (Immunofluorescence)
(Immunofluorescence of IL-36RN in rat small intestine tissue with IL-36RN antibody at 20 ug/ml.)
IHC (Immunohistochemistry)
(Anti-IL36RN / IL1F5 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
IHC (Immunohistochemistry)
(Anti-IL36RN / IL1F5 antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Related Product Information for anti-IL36RN / IL1F5 antibody
IL36RN Antibody, FIL1 Antibody, FIL1D Antibody, IL-1 delta Antibody, IL-1 related protein 3 Antibody, IL-1HY1 Antibody, IL-1RP3 Antibody, IL-1-related protein 3 Antibody, IL1F5 Antibody, IL1RP3 Antibody, IL1L1 Antibody, IL36RA Antibody, Interleukin-1 delta Antibody, Family of interleukin 1-delta Antibody, FIL1 delta Antibody, IL-1L1 Antibody, IL-1ra homolog 1 Antibody, Interleukin-1 family member 5 Antibody, Interleukin-1-like protein 1 Antibody, FIL1(DELTA) Antibody, IL-1F5 Antibody, IL1HY1 Antibody, Interleukin-1 HY1 Antibody, PSORP Antibody Description: Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,962 Da
NCBI Official Full Name
interleukin-36 receptor antagonist protein
NCBI Official Synonym Full Names
interleukin 36 receptor antagonist
NCBI Official Symbol
IL36RN
NCBI Official Synonym Symbols
FIL1; FIL1D; IL1F5; IL1L1; PSORP; IL1HY1; IL1RP3; IL36RA; IL-36Ra; PSORS14; FIL1(DELTA)
NCBI Protein Information
interleukin-36 receptor antagonist protein
UniProt Protein Name
Interleukin-36 receptor antagonist protein
UniProt Gene Name
IL36RN
UniProt Synonym Gene Names
FIL1D; IL1F5; IL1HY1; IL1L1; IL1RP3; IL-1RP3; IL-1HY1; IL-1 delta; IL-1F5; IL-1ra homolog 1; IL-1L1
UniProt Entry Name
I36RA_HUMAN
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Product Notes
The IL36RN / IL1F5 il36rn (Catalog #AAA162159) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL36RN / IL1F5 Antibody (C-Terminus) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL36RN / IL1F5 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot), IF (Immunofluorescence), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the IL36RN / IL1F5 il36rn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL36RN / IL1F5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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