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WB (Western Blot)
(Western blot analysis of Integrin alphaV expression in HeLa cells, The lane on the left is treated with the antigen-specific peptide.)
Rabbit anti-Human, Mouse Integrin alphaV Polyclonal Antibody | anti-ITGAV antibody
Integrin alphaV Antibody
Gene Names
ITGAV; CD51; MSK8; VNRA; VTNR
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Peptide affinity purification
Synonyms
Integrin alphaV, Antibody; Integrin alphaV Antibody; antigen identified by monoclonal antibody L230; CD 51; CD51; DKFZp686A08142; integrin alpha V beta 3; integrin alpha-V; Integrin alpha-V light chain; integrin alphaVbeta3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); ITAV_HUMAN; ITGAV; MSK 8; Msk8; Vitronectin receptor subunit alpha; VNRA; VTNR; anti-ITGAV antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Integrin alphaV antibody detects endogenous levels of total Integrin alphaV
Purity/Purification
Peptide affinity purification
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1002
Applicable Applications for anti-ITGAV antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide derived from human Integrin alpha V, corresponding to a region within the internal amino acids.
Conjugation
Unconjugated
Important
For western blot, incubate membrane with diluted primary Ab in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 4°C with gentle shaking, overnight.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of Integrin alphaV expression in HeLa cells, The lane on the left is treated with the antigen-specific peptide.)
WB (Western Blot)
(Western blot analysis of Integrin alphaV expression in HeLa cells, The lane on the left is treated with the antigen-specific peptide.)
IHC (Immunohistochemisry)
(AAA321830 at 1/100 staining human lung tissues sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at144 degree C.)
IHC (Immunohistochemisry)
(AAA321830 at 1/100 staining human lung tissues sections by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at144 degree C.)
IHC (Immunohiostchemistry)
(AAA321830 at 1/100 staining Human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
IHC (Immunohiostchemistry)
(AAA321830 at 1/100 staining Human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
WB (Western Blot)
(Western blot (WB) analysis of Integrin ?V expression in HeLa cells. The lane on the left was treated with the antigen-specific peptide.)
WB (Western Blot)
(Western blot (WB) analysis of Integrin ?V expression in HeLa cells. The lane on the left was treated with the antigen-specific peptide.)
Related Product Information for anti-ITGAV antibody
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
116 kDa
NCBI Official Full Name
integrin alpha-V isoform 2
NCBI Official Synonym Full Names
integrin subunit alpha V
NCBI Official Symbol
ITGAV
NCBI Official Synonym Symbols
CD51; MSK8; VNRA; VTNR
NCBI Protein Information
integrin alpha-V
UniProt Protein Name
Integrin alpha-V
UniProt Gene Name
ITGAV
UniProt Synonym Gene Names
MSK8ImportedManual assertion inferred from database entriesiHGNC:6150; VNRAImportedManual assertion inferred from database entriesiHGNC:6150; VTNRImportedManual assertion inferred from database entriesiHGNC:6150
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Product Notes
The ITGAV itgav (Catalog #AAA321830) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Integrin alphaV Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Integrin alphaV can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the ITGAV itgav for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Integrin alphaV, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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