IHC (Immunohistochemisry)
(Immunochemical staining of human ITGB3 in human breast carcinoma with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).)
Rabbit anti-Human Integrin beta 3 Polyclonal Antibody | anti-ITGB3 antibody
Anti-Integrin beta 3 Antibody, Rabbit Polyclonal
Gene Names
ITGB3; GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
Integrin beta 3, Antibody; Anti-Integrin beta 3 Antibody, Rabbit Polyclonal; Integrin beta 3/ITGB3/CD61 Antibody, Rabbit PAb, Antigen Affinity Purified; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); Anti-BDPLT16 Antibody; Anti-BDPLT2 Antibody; Anti-CD61 Antibody; Anti-GP3A Antibody; Anti-GPIIIa Antibody; Anti-GT Antibody; anti-ITGB3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human Integrin beta 3/ITGB3/CD61
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-ITGB3 antibody
IHC (Immunohistochemistry)
Immunogen
A synthetic peptide corresponding to the N-terminus of the human Integrin beta 3/ITGB3/CD61
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with A synthetic peptide corresponding to the N-terminus of the human Integrin beta 3/ITGB3/CD61, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
IHC (Immunohistochemisry)
(Immunochemical staining of human ITGB3 in human breast carcinoma with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).)
IHC (Immunohistochemisry)
(Immunochemical staining of human ITGB3 in human breast carcinoma with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).)
IHC (Immunohiostchemistry)
(Immunochemical staining of human ITGB3 in human spleen with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).)
IHC (Immunohiostchemistry)
(Immunochemical staining of human ITGB3 in human spleen with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).)
IHC (Immunohistochemistry)
(Immunochemical staining of human ITGB3 in human tonsil with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).)
IHC (Immunohistochemistry)
(Immunochemical staining of human ITGB3 in human tonsil with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-ITGB3 antibody
ITGB3 (Integrin Subunit Beta 3) is a Protein Coding gene. The ITGB3 protein product is the integrin beta chain beta 3. ITGB3 is broadly expressed in the thyroid, endometrium, and other tissues. Integrins containing the beta(3) subunit are key players in tumor growth and metastasis. ITGB3 plays an important role in ROS-induced migration and invasion in colorectal cancer (CRC). ITGB3 is translationally activated in hypoxia and regulates malignant features, including epithelial-mesenchymal transition and cell migration, through the TGF-beta pathway, revealing a novel angle for the treatment of therapy-resistant hypoxic tumors. Bioinformatic algorithms and luciferase reporter assays revealed that integrin beta3 (ITGB3) is a direct target of miR-30a-5p. Diseases associated with ITGB3 include Glanzmann Thrombasthenia and Bleeding Disorder, Platelet-Type, 16.
Product Categories/Family for anti-ITGB3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
87,058 Da
NCBI Official Full Name
integrin beta-3
NCBI Official Synonym Full Names
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
NCBI Official Symbol
ITGB3
NCBI Official Synonym Symbols
GT; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16
NCBI Protein Information
integrin beta-3; platelet membrane glycoprotein IIIa
UniProt Protein Name
Integrin beta-3
UniProt Gene Name
ITGB3
UniProt Synonym Gene Names
GP3A; GPIIIa
UniProt Entry Name
ITB3_HUMAN
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Product Notes
The ITGB3 itgb3 (Catalog #AAA254242) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Integrin beta 3 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Integrin beta 3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the ITGB3 itgb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Integrin beta 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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