IHC (Immunohistochemisry)
(Anti- MUM1 antibody, AAA46088, IHC(P)IHC(P): Human Tonsil Tissue)
Rabbit Interferon regulatory factor 4 Polyclonal Antibody | anti-IRF4 antibody
Anti-MUM1 Antibody
Gene Names
IRF4; MUM1; LSIRF; SHEP8; NF-EM5
Reactivity
Human. No cross reactivity with other proteins.
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Interferon regulatory factor 4, Antibody; Anti-MUM1 Antibody; Interferon regulatory factor 4 antibody; IRF 4 antibody; IRF-4 antibody; Irf4 antibody; IRF4_HUMAN antibody; LSIRF antibody; Lymphocyte specific interferon regulatory factor antibody; Lymphocyte specific IRF antibody; Lymphocyte-specific interferon regulatory factor antibody; Multiple myeloma oncogene 1 antibody; MUM 1 antibody; MUM1 antibody; NF EM5 antibody; NF-EM5 antibody; NFEM5 antibody; PU.1 interaction partner antibody; Sfpi1/PU.1 interaction partner antibody; Transcriptional activator PIP antibody; interferon regulatory factor 4; anti-IRF4 antibody
Host
Rabbit
Reactivity
Human. No cross reactivity with other proteins.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
450
Applicable Applications for anti-IRF4 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
E.coli-derived human MUM1 recombinant protein (Position: E272-E451). Human MUM1 shares 92% amino acid (aa) sequence identity with mouse MUM1.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemisry)
(Anti- MUM1 antibody, AAA46088, IHC(P)IHC(P): Human Tonsil Tissue)
IHC (Immunohistochemisry)
(Anti- MUM1 antibody, AAA46088, IHC(P)IHC(P): Human Tonsil Tissue)
WB (Western Blot)
(Anti- MUM1 antibody, AAA46088, Western blottingAll lanes: Anti MUM1 (AAA46088) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: JURKAT Whole Cell Lysate at 40ugPredicted bind size: 51KDObserved bind size: 40KD)
WB (Western Blot)
(Anti- MUM1 antibody, AAA46088, Western blottingAll lanes: Anti MUM1 (AAA46088) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: JURKAT Whole Cell Lysate at 40ugPredicted bind size: 51KDObserved bind size: 40KD)
WB (Western Blot)
(Anti- MUM1 antibody, AAA46088, Western blottingAll lanes: Anti MUM1 (AAA46088) at 0.5ug/mlWB: Recombinant Human MUM1 Protein 0.5ngPredicted bind size: 38KDObserved bind size: 38KD)
WB (Western Blot)
(Anti- MUM1 antibody, AAA46088, Western blottingAll lanes: Anti MUM1 (AAA46088) at 0.5ug/mlWB: Recombinant Human MUM1 Protein 0.5ngPredicted bind size: 38KDObserved bind size: 38KD)
Related Product Information for anti-IRF4 antibody
Description: Rabbit IgG polyclonal antibody for Interferon regulatory factor 4(IRF4) detection. Tested with WB, IHC-P in Human.
Background: Interferon regulatory factor 4 (IRF4), also known as MUM1, is a protein that in humans is encoded by the IRF4 gene. It is located on 6p25.3. IRF4 is a transcription factor, and it is essential for the development of T helper-2 (Th2) cells, IL17 -producing Th17 cells, and IL9 -producing Th9 cells. In melanocytic cells, the IRF4 gene may be regulated by MITF. IRF4 is a transcription factor that has been implicated in acute leukemia. This gene is strongly associated with pigmentation, sensitivity of skin to sun exposure, freckles, blue eyes, and brown hair color. What's more, IRF4 inhibition is toxic to myeloma cell lines, regardless of transforming oncogenic mechanism.
Background: Interferon regulatory factor 4 (IRF4), also known as MUM1, is a protein that in humans is encoded by the IRF4 gene. It is located on 6p25.3. IRF4 is a transcription factor, and it is essential for the development of T helper-2 (Th2) cells, IL17 -producing Th17 cells, and IL9 -producing Th9 cells. In melanocytic cells, the IRF4 gene may be regulated by MITF. IRF4 is a transcription factor that has been implicated in acute leukemia. This gene is strongly associated with pigmentation, sensitivity of skin to sun exposure, freckles, blue eyes, and brown hair color. What's more, IRF4 inhibition is toxic to myeloma cell lines, regardless of transforming oncogenic mechanism.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
51,644 Da
NCBI Official Full Name
interferon regulatory factor 4 isoform 2
NCBI Official Synonym Full Names
interferon regulatory factor 4
NCBI Official Symbol
IRF4
NCBI Official Synonym Symbols
MUM1; LSIRF; SHEP8; NF-EM5
NCBI Protein Information
interferon regulatory factor 4; multiple myeloma oncogene 1; lymphocyte-specific interferon regulatory factor
UniProt Protein Name
Interferon regulatory factor 4
UniProt Gene Name
IRF4
UniProt Synonym Gene Names
MUM1; IRF-4; LSIRF
UniProt Entry Name
IRF4_HUMAN
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Product Notes
The IRF4 irf4 (Catalog #AAA46088) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MUM1 Antibody reacts with Human. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Interferon regulatory factor 4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the IRF4 irf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interferon regulatory factor 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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