IHC (Immunohiostchemistry)
(Immunohistochemistry of IQSEC2 in mouse brain tissue with IQSEC2 antibody at 5 μg/ml.)
Rabbit IQSEC2 Polyclonal Antibody | anti-IQSEC2 antibody
IQSEC2 Antibody
Gene Names
IQSEC2; MRX1; BRAG1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
IQSEC2 antibody is affinity chromatography purified via peptide column.
Synonyms
IQSEC2, Antibody; IQSEC2 Antibody; IQ motif and Sec7 domain 2; Brefeldin-resistant Arf-GEF 1 protein; BRAG1; MRX1; anti-IQSEC2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
IQSEC2 antibody is human, mouse and rat reactive. At least two isoforms of IQSEC2 are known to exist; this antibody will only detect the larger isoform. IQSEC2 antibody is predicted to not cross-react with IQSEC1.
Purity/Purification
IQSEC2 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1488
Applicable Applications for anti-IQSEC2 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
IQSEC2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IQSEC2.
Buffer
IQSEC2 antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
IQSEC2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IHC (Immunohiostchemistry)
(Immunohistochemistry of IQSEC2 in mouse brain tissue with IQSEC2 antibody at 5 μg/ml.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of IQSEC2 in mouse brain tissue with IQSEC2 antibody at 5 μg/ml.)
WB (Western Blot)
(Western blot analysis of IQSEC2 in SK-N-SH cell lysate with IQSEC2 antibody at 1 μg/ml.)
WB (Western Blot)
(Western blot analysis of IQSEC2 in SK-N-SH cell lysate with IQSEC2 antibody at 1 μg/ml.)
Related Product Information for anti-IQSEC2 antibody
ADP ribosylation factors (Arfs) are small GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of coat protein complexes at sites of carrier vesicle formation. Similar to the related protein IQSEC1, IQSEC2 is a guanine nucleotide exchange protein for ARF1 and ARF6 that belongs to the BRAG family and contains one IQ domain, one PH domain and one SEC7 domain (1,2). IQSEC2 is a major component of the postsynaptic density (PSD) and colocalizes with PSD-95. It has been suggested to modulate the functions of the ARF proteins (1). Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation (3).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 104; 133; 141; 164 kDa
Observed: 140 kDa
Observed: 140 kDa
NCBI Official Full Name
IQ motif and SEC7 domain-containing protein 2 isoform 1
NCBI Official Synonym Full Names
IQ motif and Sec7 domain 2
NCBI Official Symbol
IQSEC2
NCBI Official Synonym Symbols
MRX1; BRAG1
NCBI Protein Information
IQ motif and SEC7 domain-containing protein 2; brefeldin A resistant Arf-guanine nucleotide exchange factor 1; brefeldin A resistant Arf-guanine nucleotide exchange factor 1b; brefeldin A resistant Arf-guanine nucleotide exchange factor 1c
UniProt Protein Name
IQ motif and SEC7 domain-containing protein 2
UniProt Gene Name
IQSEC2
UniProt Synonym Gene Names
KIAA0522
UniProt Entry Name
IQEC2_HUMAN
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Product Notes
The IQSEC2 iqsec2 (Catalog #AAA40559) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IQSEC2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IQSEC2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the IQSEC2 iqsec2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IQSEC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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