IHC (Immunohiostchemistry)
(IRGM Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IRGM Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human IRGM Polyclonal Antibody | anti-IRGM antibody
IRGM Antibody (C-term)
Gene Names
IRGM; IFI1; IRGM1; LRG47; LRG-47
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
IRGM, Antibody; IRGM Antibody (C-term); Immunity-related GTPase family M protein; 365-; Immunity-related GTPase family M protein 1; Interferon-inducible protein 1; LPS-stimulated RAW 2647 macrophage protein 47 homolog; LRG-47; IRGM; IFI1; IRGM1; LRG47; anti-IRGM antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This IRGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-179 amino acids from the C-terminal region of human IRGM.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.35 (varies by lot)
Sequence Positions
151-179
Sequence Length
181
Applicable Applications for anti-IRGM antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(IRGM Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IRGM Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(IRGM Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IRGM Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(IRGM Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IRGM antibody detected the IRGM protein (arrow).)
WB (Western Blot)
(IRGM Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IRGM antibody detected the IRGM protein (arrow).)
Related Product Information for anti-IRGM antibody
This gene encodes a member of the p47 immunity-related
GTPase family. The encoded protein may play a role in the innate
immune response by regulating autophagy formation in response to
intracellular pathogens. Polymorphisms that affect the normal
expression of this gene are associated with a susceptibility to
Crohn's disease and tuberculosis.
GTPase family. The encoded protein may play a role in the innate
immune response by regulating autophagy formation in response to
intracellular pathogens. Polymorphisms that affect the normal
expression of this gene are associated with a susceptibility to
Crohn's disease and tuberculosis.
Product Categories/Family for anti-IRGM antibody
References
Che, N., et al. Clin. Chim. Acta 411 (21-22), 1645-1649 (2010) :
Wolfkamp, S.C., et al. Eur J Gastroenterol Hepatol 22(8):933-937(2010)
Latiano, A., et al. Inflamm. Bowel Dis. 16(7):1108-1117(2010)
Prescott, N.J., et al. Hum. Mol. Genet. 19(9):1828-1839(2010)
Bekpen, C., et al. PLoS Genet. 5 (3), E1000403 (2009) :
Wolfkamp, S.C., et al. Eur J Gastroenterol Hepatol 22(8):933-937(2010)
Latiano, A., et al. Inflamm. Bowel Dis. 16(7):1108-1117(2010)
Prescott, N.J., et al. Hum. Mol. Genet. 19(9):1828-1839(2010)
Bekpen, C., et al. PLoS Genet. 5 (3), E1000403 (2009) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20142
NCBI Official Full Name
immunity-related GTPase family M protein
NCBI Official Synonym Full Names
immunity-related GTPase family, M
NCBI Official Symbol
IRGM
NCBI Official Synonym Symbols
IFI1; IRGM1; LRG47; LRG-47
NCBI Protein Information
immunity-related GTPase family M protein
UniProt Protein Name
Immunity-related GTPase family M protein
UniProt Gene Name
IRGM
UniProt Synonym Gene Names
IFI1; IRGM1; LRG47; LRG-47
UniProt Entry Name
IRGM_HUMAN
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Product Notes
The IRGM irgm (Catalog #AAA284125) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 151-179. The IRGM Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IRGM can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the IRGM irgm for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IRGM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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