Rabbit anti-Human Irisin Polyclonal Antibody | anti-FNDC5 antibody
Irisin (human) polyclonal antibody
Gene Names
FNDC5; FRCP2; irisin
Reactivity
Human
Applications
Western Blot, Immunoprecipitation, ELISA
Purity
Protein A affinity purified and immuno depleted
Synonyms
Irisin, Antibody; Irisin (human) polyclonal antibody; anti-FNDC5 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Protein A affinity purified and immuno depleted
Form/Format
Liquid. In PBS containing 50% glycerol and 0.09% sodium azide
Applicable Applications for anti-FNDC5 antibody
WB (Western Blot), IP (Immunoprecipitation), ELISA
Source Note
Purified from rabbit serum
Immunogen
Recombinant human Irisin (active)
Preparation and Storage
Long term Storage: -20°C.
Short Term : -20°C . Avoid freeze/thaw cycles.
Short Term : -20°C . Avoid freeze/thaw cycles.
Related Product Information for anti-FNDC5 antibody
Irisin is a hormone that is involved in converting white adipose tissue into brown adipose tissue after physical exercise. It is formed after the membrane bound protein fibronectin type III domain containing protein 5 (FNDC5) is cleaved resulting in a secreted protein. FNDC5 is found in muscle tissue and is activated during physical exertion via the protein PGC1a. Soluble Irisin has also been shown to up regulate UCP-1 gene expression in mice. UCP-1 is a mitochondrial transporter protein and a marker of brown adipose tissue conversion. This suggests that Irisin plays an important role in energy regulation and furthermore may lead to improvements in glucose regulation, insulin sensitivity, hypertension, and obesity.
Product Categories/Family for anti-FNDC5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15,527 Da
NCBI Official Full Name
fibronectin type III domain-containing protein 5 isoform 3 preproprotein
NCBI Official Synonym Full Names
fibronectin type III domain containing 5
NCBI Official Symbol
FNDC5
NCBI Official Synonym Symbols
FRCP2; irisin
NCBI Protein Information
fibronectin type III domain-containing protein 5; fibronectin type III repeat-containing protein 2
UniProt Protein Name
Fibronectin type III domain-containing protein 5
UniProt Gene Name
FNDC5
UniProt Synonym Gene Names
FRCP2
UniProt Entry Name
FNDC5_HUMAN
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Product Notes
The FNDC5 fndc5 (Catalog #AAA77055) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Irisin (human) polyclonal antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Irisin can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), ELISA. Researchers should empirically determine the suitability of the FNDC5 fndc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Irisin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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