WB (Western Blot)
(Anti-ITGA7 Antibody (N-term)at 1:4000 dilution + A431 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 129 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human ITGA7 Polyclonal Antibody | anti-ITGA7 antibody
ITGA7 Antibody (N-term)
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ITGA7, Antibody; ITGA7 Antibody (N-term); Integrin alpha-7; Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form; ITGA7; anti-ITGA7 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ITGA7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 247-279 amino acids from the N-terminal region of human ITGA7.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Length
1141
Applicable Applications for anti-ITGA7 antibody
ELISA, WB (Western Blot)
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Anti-ITGA7 Antibody (N-term)at 1:4000 dilution + A431 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 129 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(Anti-ITGA7 Antibody (N-term)at 1:4000 dilution + A431 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 129 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(All lanes : Anti-ITGA7 Antibody (N-term) at 1:2000 dilutionLane 1: Hela whole cell lysatesLane 2: A431 whole cell lysatesLane 3: Jurkat whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 129 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(All lanes : Anti-ITGA7 Antibody (N-term) at 1:2000 dilutionLane 1: Hela whole cell lysatesLane 2: A431 whole cell lysatesLane 3: Jurkat whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 129 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-ITGA7 antibody
Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.
References
Leung E.,et al.Biochem. Biophys. Res. Commun. 243:317-325(1998).
Hayashi Y.K.,et al.Nat. Genet. 19:94-97(1998).
Vizirianakis I.S.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Vignier N.,et al.Biochem. Biophys. Res. Commun. 260:357-364(1999).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Hayashi Y.K.,et al.Nat. Genet. 19:94-97(1998).
Vizirianakis I.S.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
Vignier N.,et al.Biochem. Biophys. Res. Commun. 260:357-364(1999).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
128948
NCBI Official Full Name
integrin alpha-7 isoform 1
NCBI Official Synonym Full Names
integrin, alpha 7
NCBI Official Symbol
ITGA7
NCBI Protein Information
integrin alpha-7
UniProt Protein Name
Integrin alpha-7
UniProt Gene Name
ITGA7
UniProt Entry Name
ITA7_HUMAN
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Product Notes
The ITGA7 itga7 (Catalog #AAA283707) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ITGA7 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ITGA7 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the ITGA7 itga7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ITGA7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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