IHC (Immunohiostchemistry)
(ITGA8 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITGA8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human ITGA8 Polyclonal Antibody | anti-ITGA8 antibody
ITGA8 Antibody (C-term)
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ITGA8, Antibody; ITGA8 Antibody (C-term); Integrin alpha-8; Integrin alpha-8 heavy chain; Integrin alpha-8 light chain; ITGA8; anti-ITGA8 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ITGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1053 amino acids from the C-terminal region of human ITGA8.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.29 (varies by lot)
Sequence Positions
1025-1053
Sequence Length
1,063
Applicable Applications for anti-ITGA8 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Cellular Location
Membrane; Single-pass type I membrane protein Cell membrane
Tissue Location
Expressed in mesenchymal cells, including alveolar myofibroblasts, kidney mesangial cells and hepatic stellar cells and vascular and visceral smooth muscle (at protein level).
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(ITGA8 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITGA8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(ITGA8 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITGA8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(ITGA8 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ITGA8 antibody detected the ITGA8 protein (arrow).)
WB (Western Blot)
(ITGA8 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ITGA8 antibody detected the ITGA8 protein (arrow).)
Related Product Information for anti-ITGA8 antibody
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.
Product Categories/Family for anti-ITGA8 antibody
References
Benoit, Y.D., et al. Biochem. Biophys. Res. Commun. 399(3):434-439(2010)
Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009)
Benoit, Y.D., et al. Biol. Cell 101(12):695-708(2009)
Sato, Y., et al. J. Biol. Chem. 284(21):14524-14536(2009)
Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) :
Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009)
Benoit, Y.D., et al. Biol. Cell 101(12):695-708(2009)
Sato, Y., et al. J. Biol. Chem. 284(21):14524-14536(2009)
Lowe, J.K., et al. PLoS Genet. 5 (2), E1000365 (2009) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
117474
NCBI Official Full Name
integrin alpha-8
NCBI Official Synonym Full Names
integrin, alpha 8
NCBI Official Symbol
ITGA8
NCBI Protein Information
integrin alpha-8
UniProt Protein Name
Integrin alpha-8
UniProt Gene Name
ITGA8
UniProt Entry Name
ITA8_HUMAN
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Product Notes
The ITGA8 itga8 (Catalog #AAA287894) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1025-1053. The ITGA8 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ITGA8 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the ITGA8 itga8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ITGA8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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