IHC (Immunohiostchemistry)
(ITGB5 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITGB5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit ITGB5 Polyclonal Antibody | anti-ITGB5 antibody
ITGB5 Antibody (N-term)
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ITGB5, Antibody; ITGB5 Antibody (N-term); Integrin beta-5; ITGB5; anti-ITGB5 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ITGB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-244 amino acids from the N-terminal region of human ITGB5.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
0.44mg/ml (varies by lot)
Sequence Positions
216-244
Sequence Length
799
Applicable Applications for anti-ITGB5 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Function
Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Cellular Location
Membrane; Single-pass type I membrane protein
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(ITGB5 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITGB5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(ITGB5 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITGB5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(ITGB5 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ITGB5 antibody detected the ITGB5 protein (arrow).)
WB (Western Blot)
(ITGB5 Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the ITGB5 antibody detected the ITGB5 protein (arrow).)
Related Product Information for anti-ITGB5 antibody
Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
Product Categories/Family for anti-ITGB5 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Li, Z., et al. J. Biol. Chem. 285(31):23699-23710(2010)
Leifheit-Nestler, M., et al. Arterioscler. Thromb. Vasc. Biol. 30(7):1398-1406(2010)
Lane, D., et al. Oncogene 29(24):3519-3531(2010)
Lyle, C., et al. Virol. J. 7, 148 (2010) :
Li, Z., et al. J. Biol. Chem. 285(31):23699-23710(2010)
Leifheit-Nestler, M., et al. Arterioscler. Thromb. Vasc. Biol. 30(7):1398-1406(2010)
Lane, D., et al. Oncogene 29(24):3519-3531(2010)
Lyle, C., et al. Virol. J. 7, 148 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
88054
NCBI Official Full Name
integrin beta-5
NCBI Official Synonym Full Names
integrin, beta 5
NCBI Official Symbol
ITGB5
NCBI Protein Information
integrin beta-5
UniProt Protein Name
Integrin beta-5
UniProt Gene Name
ITGB5
UniProt Entry Name
ITB5_HUMAN
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Product Notes
The ITGB5 itgb5 (Catalog #AAA286952) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 216-244. The ITGB5 Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's ITGB5 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the ITGB5 itgb5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ITGB5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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