IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Rabbit anti-Human Jagged 2 (JAG2) Polyclonal Antibody | anti-JAG2 antibody
Jagged 2 (JAG2) Antibody (C-term)
Gene Names
JAG2; HJ2; SER2
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Jagged 2 (JAG2), Antibody; Jagged 2 (JAG2) Antibody (C-term); Protein jagged-2; Jagged2; hJ2; JAG2; anti-JAG2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Jagged 2 (JAG2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1209-1238 amino acids from the C-terminal region of human Jagged 2 (JAG2).
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
1209-1238
Sequence Length
1,200
Applicable Applications for anti-JAG2 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
WB (Western Blot)
(Western blot analysis of Jag2 (arrow) using JAG2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the JAG2 gene (Lane 2) (Origene Technologies).)
WB (Western Blot)
(Western blot analysis of Jag2 (arrow) using JAG2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the JAG2 gene (Lane 2) (Origene Technologies).)
Related Product Information for anti-JAG2 antibody
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors.
Product Categories/Family for anti-JAG2 antibody
References
Hayashi, T., et al., J. Androl. 22(6):999-1011 (2001).
Lindner, V., et al., Am. J. Pathol. 159(3):875-883 (2001).
Cereseto, A., et al., J. Cell. Physiol. 185(3):425-431 (2000).
Tsai, S., et al., Blood 96(3):950-957 (2000).
Deng, Y., et al., Genomics 63(1):133-138 (2000).
Lindner, V., et al., Am. J. Pathol. 159(3):875-883 (2001).
Cereseto, A., et al., J. Cell. Physiol. 185(3):425-431 (2000).
Tsai, S., et al., Blood 96(3):950-957 (2000).
Deng, Y., et al., Genomics 63(1):133-138 (2000).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
133367
NCBI Official Full Name
protein jagged-2 isoform a
NCBI Official Synonym Full Names
jagged 2
NCBI Official Symbol
JAG2
NCBI Official Synonym Symbols
HJ2; SER2
NCBI Protein Information
protein jagged-2
UniProt Protein Name
Protein jagged-2
UniProt Gene Name
JAG2
UniProt Synonym Gene Names
Jagged2; hJ2
UniProt Entry Name
JAG2_HUMAN
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Product Notes
The JAG2 jag2 (Catalog #AAA286633) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1209-1238. The Jagged 2 (JAG2) Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Jagged 2 (JAG2) can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the JAG2 jag2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Jagged 2 (JAG2), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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