Skip to main content
Call us at +1-800-604-9114 for more information about our products or contact us online
Cart Login
product-image-AAA29054_IHC7.jpg
IHC (Immunohistochemistry)
>
<
product-image-AAA29054_IHC6.jpg
product-image-AAA29054_IHC5.jpg
product-image-AAA29054_IHC4.jpg
product-image-AAA29054_IHC3.jpg
product-image-AAA29054_APP2.jpg
product-image-AAA29054_WB.jpg

Rabbit JAK3 Polyclonal Antibody | anti-JAK3 antibody

JAK3 Polyclonal Antibody

Gene Names
JAK3; JAKL; LJAK; JAK-3; L-JAK; JAK3_HUMAN
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Synonyms
JAK3, Antibody; JAK3 Polyclonal Antibody; JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK; anti-JAK3 antibody
Ordering
 
When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures.
 
When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures.
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Applicable Applications for anti-JAK3 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohistochemistry)

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.)

IHC (Immunohistchemistry)

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.)

IHC (Immunohistochemistry)

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.)

IHC (Immunohistochemistry-Paraffin)

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.)

IHC (Immunohistochemistry-Paraffin)

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.)

Application Data

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.)

WB (Western Blot)

(Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.)

Related Product Information for anti-JAK3 antibody
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, or differentiation. Mediates essential signaling events in both innate and adaptive immunity and plays a crucial role in hematopoiesis during T-cells development. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors sharing the common subunit gamma such as IL2R, IL4R, IL7R, IL9R, IL15R and IL21R. Following ligand binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor. Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, upon IL2R activation by IL2, JAK1 and JAK3 molecules bind to IL2R beta (IL2RB) and gamma chain (IL2RG) subunits inducing the tyrosine phosphorylation of both receptor subunits on their cytoplasmic domain. Then, STAT5A AND STAT5B are recruited, phosphorylated and activated by JAK1 and JAK3. Once activated, dimerized STAT5 translocates to the nucleus and promotes the transcription of specific target genes in a cytokine-specific fashion.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
125,099 Da
NCBI Official Full Name
tyrosine-protein kinase JAK3
NCBI Official Synonym Full Names
Janus kinase 3
NCBI Official Symbol
JAK3
NCBI Official Synonym Symbols
JAKL; LJAK; JAK-3; L-JAK; JAK3_HUMAN
NCBI Protein Information
tyrosine-protein kinase JAK3; leukocyte Janus kinase; Janus kinase 3 (a protein tyrosine kinase, leukocyte)
UniProt Protein Name
Tyrosine-protein kinase JAK3
UniProt Gene Name
JAK3
UniProt Synonym Gene Names
JAK-3; L-JAK
UniProt Entry Name
JAK3_HUMAN

Similar Products

product-image-AAA29054_IHC7.jpg

JAK3 Antibody

Host: Rabbit
Reactivity: Human, Mouse, Rat
Apps: Western Blot, Immunohistochemistry, Immunofluorescence
product-image-AAA31404_APP6.jpg

JAK3 Antibody

Host: Rabbit
Reactivity: Human, Mouse, Rat
Predicted Reactivity: Bovine (100%), Sheep (100%), Dog (100%)
Apps: Western Blot, Immunohistochemistry, Immunofluorescence, Immunocytochemistry, ELISA
product-image-AAA31405_APP9.jpg

JAK3 Antibody

Host: Rabbit
Reactivity: Human, Mouse, Rat, Monkey
Predicted Reactivity: Pig (100%), Bovine (91%), Horse (100%), Sheep (100%), Dog (100%)
Apps: Western Blot, Immunohistochemistry, Immunofluorescence, Immunocytochemistry, ELISA
product-image-AAA16530_SC.jpg

OVA slgE ELISA Kit

Host: n/a
Reactivity: Mouse
Apps: n/a
product-image-AAA17043_SC.jpg

OVA sIgG ELISA Kit

Host: n/a
Reactivity: Porcine
Apps: n/a
product-image-AAA16369_SC.jpg

OVA sIgG ELISA Kit

Host: n/a
Reactivity: Guinea Pig
Apps: n/a
product-image-AAA16694_SC.jpg

OVA sIgG1 ELISA Kit

Host: n/a
Reactivity: Mouse
Apps: n/a
product-image-AAA20826_WB.jpg

OVA Antibody

Host: Mouse
Reactivity: Pan-species (General)
Apps: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
product-image-AAA17700_SC.jpg

OVA SIgM ELISA Kit

Host: n/a
Reactivity: Rat
Apps: n/a
product-image-AAA17619_SC.jpg

OVA sIgE ELISA Kit

Host: n/a
Reactivity: Mouse
Apps: n/a
product-image-AAA17575_SC.jpg

OVA sIgG ELISA Kit

Host: n/a
Reactivity: Mouse
Apps: n/a
product-image-AAA20053_SC.jpg

OVA ELISA Kit

Host: n/a
Reactivity: General
Apps: n/a
product-image-AAA27613_SC.jpg

OVA ELISA Kit

Host: n/a
Reactivity: Chicken
Apps: n/a
product-image-AAA22346_SC.jpg

OVA sIgA ELISA Kit

Host: n/a
Reactivity: Mouse
Apps: n/a
product-image-AAA23111_SC.jpg

OVA ELISA Kit

Host: n/a
Reactivity: General
Apps: ELISA
product-image-AAA21095_WB.jpg

OVA Antibody

Host: Rabbit
Reactivity: Pan-species (General)
Apps: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
product-image-AAA23756_SC.jpg

OVA-sIgG ELISA Kit

Host: n/a
Reactivity: Rat
Apps: n/a
product-image-AAA16976_SC.jpg

IgE ELISA Kit

Host: n/a
Reactivity: Porcine
Apps: n/a
product-image-AAA17586_SC.jpg

IgE ELISA Kit

Host: n/a
Reactivity: Guinea pig
Apps: n/a

Product Notes

The JAK3 jak3 (Catalog #AAA29054) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JAK3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's JAK3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF). Researchers should empirically determine the suitability of the JAK3 jak3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JAK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.