WB (Western Blot)
(Western blot analysis of JNK p46 and JNK p54 expression in K-562 (A), A-431 (B), NIH/3T3 (C), HeLa (D), RAW264.7 (E) and Jurkat (F) whole cell lysates.)
Rabbit JNK Polyclonal Antibody | anti-JNK antibody
JNK Antibody
Gene Names
MAPK8; JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
Reactivity
Human, Mouse, Rat
Applications
Flow Cytometry, Functional Assay, Immunofluorescence, Immunoprecipitation, Western Blot
Purity
Immunogen affinity purified
Synonyms
JNK, Antibody; JNK Antibody; AI849689 antibody; c Jun N terminal kinase 1 antibody; C-JUN kinase 1 antibody; c-Jun N-terminal kinase 1 antibody; EC 2.7.11.24 antibody; JNK 1 antibody; JNK antibody; JNK-46 antibody; JNK1A2 antibody; JNK21B1/2 antibody; MAP kinase 8 antibody; MAPK 8 antibody; mapk8 antibody; Mitogen activated protein kinase 8 antibody; Mitogen-activated protein kinase 8 antibody; MK08_HUMAN antibody; p54 gamma antibody; Prkm8 antibody; Protein kinase JNK1 antibody; Protein kinase; mitogen-activated; 8 antibody; SAPK 1 antibody; SAPK gamma antibody; SAPK1 antibody; Stress-activated protein kinase 1 antibody; Stress-activated protein kinase JNK1 antibody; anti-JNK antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Immunogen affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-JNK antibody
FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IP (Immunoprecipitation), WB (Western Blot)
Immunogen
Amino acids 1-384 representing full length JNK1 of human origin.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
WB (Western Blot)
(Western blot analysis of JNK p46 and JNK p54 expression in K-562 (A), A-431 (B), NIH/3T3 (C), HeLa (D), RAW264.7 (E) and Jurkat (F) whole cell lysates.)
WB (Western Blot)
(Western blot analysis of JNK p46 and JNK p54 expression in K-562 (A), A-431 (B), NIH/3T3 (C), HeLa (D), RAW264.7 (E) and Jurkat (F) whole cell lysates.)
WB (Western Blot)
(Western blot analysis of JNK phosphorylation in untreated (A, D), anisomycin treated (B, E) and anisomycin and lambda protein phosphatasetreated (C, F) Jurkat whole cell lysates.)
WB (Western Blot)
(Western blot analysis of JNK phosphorylation in untreated (A, D), anisomycin treated (B, E) and anisomycin and lambda protein phosphatasetreated (C, F) Jurkat whole cell lysates.)
Related Product Information for anti-JNK antibody
c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield ten isoforms through alternative mRNA splicing, including JNK1alpha1, JNK1beta 1, JNK2alpha1, JNK2beta 1 and JNK3alpha1, which represent the p46 isoforms, and JNK1alpha2, JNK1beta 2, JNK2alpha2, JNK2beta 2 and JNK3beta 2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in Ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun and other signaling kinases, including MEKK1 and p38.
Product Categories/Family for anti-JNK antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
427
NCBI Official Full Name
Mitogen-activated protein kinase 8
NCBI Official Synonym Full Names
mitogen-activated protein kinase 8
NCBI Official Symbol
MAPK8
NCBI Official Synonym Symbols
JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
NCBI Protein Information
mitogen-activated protein kinase 8; MAP kinase 8; JUN N-terminal kinase; c-Jun N-terminal kinase 1; stress-activated protein kinase 1; stress-activated protein kinase 1c; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kin
UniProt Protein Name
Mitogen-activated protein kinase 8
UniProt Gene Name
MAPK8
UniProt Synonym Gene Names
JNK1; PRKM8; SAPK1; SAPK1C; MAP kinase 8; MAPK 8; SAPK1c
UniProt Entry Name
MK08_HUMAN
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Product Notes
The JNK mapk8 (Catalog #AAA312000) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The JNK Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's JNK can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the JNK mapk8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JNK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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