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IHC (Immunohistchemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(F)IHC(F): Rat Intestine Tissue)
Rabbit Junction plakoglobin Polyclonal Antibody | anti-JUP antibody
Anti-gamma Catenin Antibody
Gene Names
JUP; DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12
Reactivity
Human, Mouse, Rat. No cross reactivity with other proteins.
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry
Purity
Immunogen affinity purified.
Synonyms
Junction plakoglobin, Antibody; Anti-gamma Catenin Antibody; ARVD 12 antibody; ARVD12 antibody; Catenin (cadherin associated protein) gamma 80kDa antibody; Catenin (cadherin associated protein), gamma 80kDa antibody; catenin (cadherin-associated protein) gamma (80kD) antibody; Catenin gamma 80kDa antibody; Catenin gamma antibody; CTNNG antibody; Desmoplakin 3 antibody; Desmoplakin III antibody; Desmoplakin-3 antibody; Desmoplakin3 antibody; DesmoplakinIII antibody; DP 3 antibody; DP III antibody; DP3 antibody; DPIII antibody; Gamma catenin antibody; Junction plakoglobin antibody; JUP antibody; OTTHUMP00000164732 antibody; OTTHUMP00000164735 antibody; OTTHUMP00000164738 antibody; PDGB antibody; PKGB antibody; PLAK_HUMAN antibody; PLAKOGLOBIN antibody; junction plakoglobin; anti-JUP antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat. No cross reactivity with other proteins.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
745
Applicable Applications for anti-JUP antibody
Western Blot (WB), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-F)
Application Notes
Western Blot: Concentration: 0.1-0.5mug/ml; Tested Species: Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section): Concentration: 0.5-1mug/ml; Tested Species: Human, Mouse, Rat
Immunohistochemistry (Frozen Section): Concentration: 0.5-1mug/ml; Tested Species: Rat; Predicted Species: Human
Immunohistochemistry (Paraffin-embedded Section): Concentration: 0.5-1mug/ml; Tested Species: Human, Mouse, Rat
Immunohistochemistry (Frozen Section): Concentration: 0.5-1mug/ml; Tested Species: Rat; Predicted Species: Human
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
E.coli-derived human gamma Catenin recombinant protein (Position: M556-A745). Human gamma Catenin shares 98% amino acid (aa) sequence identity with both mouse and rat gamma Catenin.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistchemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(F)IHC(F): Rat Intestine Tissue)
IHC (Immunohistchemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(F)IHC(F): Rat Intestine Tissue)
IHC (Immunohistochemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(P)IHC(P): Rat Intestine Tissue)
IHC (Immunohistochemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(P)IHC(P): Rat Intestine Tissue)
IHC (Immunohistochemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(P)IHC(P): Mouse Intestine Tissue)
IHC (Immunohistochemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(P)IHC(P): Mouse Intestine Tissue)
IHC (Immunohistochemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
IHC (Immunohistochemistry)
(Anti- gamma Catenin Picoband antibody, AAA11635, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
WB (Western Blot)
(Anti- gamma Catenin Picoband antibody, AAA11635, Western blottingAll lanes: Anti gamma Catenin (AAA11635) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Rat Cardiac Muscle Tissue Lysate at 50ugLane 3: Rat Thymus Tissue Lysate at 50ugLane 4: RH35 Whole Cell Lysate at 40ugLane 5: Hela Whole Cell Lysate at 40ugLane 6: Colo320 Whole Cell Lysate at 40ugLane 7: HepG2 Whole Cell Lysate at 40ugLane 8: HepA Whole Cell Lysate at 40ugLane 9: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 81KD Observed bind size: 81KD)
WB (Western Blot)
(Anti- gamma Catenin Picoband antibody, AAA11635, Western blottingAll lanes: Anti gamma Catenin (AAA11635) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Rat Cardiac Muscle Tissue Lysate at 50ugLane 3: Rat Thymus Tissue Lysate at 50ugLane 4: RH35 Whole Cell Lysate at 40ugLane 5: Hela Whole Cell Lysate at 40ugLane 6: Colo320 Whole Cell Lysate at 40ugLane 7: HepG2 Whole Cell Lysate at 40ugLane 8: HepA Whole Cell Lysate at 40ugLane 9: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 81KD Observed bind size: 81KD)
WB (Western Blot)
(Anti- gamma Catenin Picoband antibody, AAA11635, Western blottingAll lanes: Anti gamma Catenin(AAA11635) at 0.5ug/mlWB: Recombinant Human gamma Catenin Protein 0.5ngPredicted bind size: 47KDObserved bind size: 47KD)
WB (Western Blot)
(Anti- gamma Catenin Picoband antibody, AAA11635, Western blottingAll lanes: Anti gamma Catenin(AAA11635) at 0.5ug/mlWB: Recombinant Human gamma Catenin Protein 0.5ngPredicted bind size: 47KDObserved bind size: 47KD)
Related Product Information for anti-JUP antibody
Description: Rabbit IgG polyclonal antibody for Junction plakoglobin(JUP) detection. Tested with WB, IHC-P, IHC-F in Human;Mouse;Rat.
Background: Junction plakoglobin(JUP), also known as gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to beta-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Meanwhile, JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.
Background: Junction plakoglobin(JUP), also known as gamma-catenin, is a protein that in humans is encoded by the JUP gene. It is a member of the catenin protein family and homologous to beta-catenin, and it is mapped to 17q21.2. This gene encodes a major cytoplasmic protein that is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins. Meanwhile, JUP may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
81,745 Da
NCBI Official Full Name
junction plakoglobin
NCBI Official Synonym Full Names
junction plakoglobin
NCBI Official Symbol
JUP
NCBI Official Synonym Symbols
DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12
NCBI Protein Information
junction plakoglobin; desmoplakin-3; desmoplakin III; catenin (cadherin-associated protein), gamma 80kDa
UniProt Protein Name
Junction plakoglobin
UniProt Gene Name
JUP
UniProt Synonym Gene Names
CTNNG; DP3
UniProt Entry Name
PLAK_HUMAN
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Product Notes
The JUP jup (Catalog #AAA11635) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-gamma Catenin Antibody reacts with Human, Mouse, Rat. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Junction plakoglobin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-F). Western Blot: Concentration: 0.1-0.5mug/ml; Tested Species: Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section): Concentration: 0.5-1mug/ml; Tested Species: Human, Mouse, Rat Immunohistochemistry (Frozen Section): Concentration: 0.5-1mug/ml; Tested Species: Rat; Predicted Species: Human. Researchers should empirically determine the suitability of the JUP jup for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Junction plakoglobin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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