Application Data
(Fig: Western blot analysis on mouse heart using anti-JPH-2 polyclonal antibody)
Junctophilin-2 Polyclonal Antibody | anti-JPH2 antibody
Junctophilin-2 Antibody
Gene Names
JPH2; JP2; JP-2; CMH17
Reactivity
Mouse, Rat, Human
Applications
Immunocytochemistry, Western Blot
Purity
Affinity purified
Synonyms
Junctophilin-2, Antibody; Junctophilin-2 Antibody; anti-JPH2 antibody
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of mouse Junctophilin-2.
Purity/Purification
Affinity purified
Form/Format
Liquid; 1*TBS (pH7.4), 0.5%BSA, 25% Glycerol.
Concentration
0.5mg/ml (varies by lot)
Sequence Length
696
Applicable Applications for anti-JPH2 antibody
ICC (Immunocytochemistry), WB (Western Blot)
Preservative
0.05% Sodium Azide.
Cellular Localization
Cell Membrane; ER Membrane
Positive Control
Mouse Heart
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
Application Data
(Fig: Western blot analysis on mouse heart using anti-JPH-2 polyclonal antibody)
Application Data
(Fig: Western blot analysis on mouse heart using anti-JPH-2 polyclonal antibody)
Related Product Information for anti-JPH2 antibody
Junctophilin-2 (JPH2) is a cardiac specific member of the junctophilins, a newly characterized family of junctional membrane complex proteins important in physically approximating the plasmalemmal L-type calcium channel and the sarcoplasmic reticulum ryanodine receptor for calcium-induced calcium release. It acts probably by anchoring the plasma membrane and endoplasmic reticulum. JPH2 contributes to the construction of skeletal muscle triad junctions, and plays an essential role in heart development.
References
1. Takeshima, H., et al. 2.00. Junctophilins: a novel family of junctional membrane complex proteins. Mol. Cell 6: 1.-2. 2. Nishi, M., et al. 2.03. Coexpression of Junctophilin type 3.and type 4 in brain. Brain Res. Mol. Brain Res. 1.8: 1.2.1.0.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
94; 74kDa
NCBI Official Full Name
junctophilin-2 isoform 1
NCBI Official Synonym Full Names
junctophilin 2
NCBI Official Symbol
JPH2
NCBI Official Synonym Symbols
JP2; JP-2; CMH17
NCBI Protein Information
junctophilin-2
UniProt Protein Name
Junctophilin-2
UniProt Gene Name
JPH2
UniProt Synonym Gene Names
JP2; JP-2
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Product Notes
The JPH2 jph2 (Catalog #AAA111170) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Junctophilin-2 Antibody reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Junctophilin-2 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the JPH2 jph2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Junctophilin-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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