ICC (Immunocytochemistry)
(Anti-Kallikrein 6 antibody, AAA45162, ICCICC: PC-3 Cell)
Rabbit anti-Human Kallikrein 6 Polyclonal Antibody | anti-KLK6 antibody
Anti-Kallikrein 6 antibody
Gene Names
KLK6; hK6; Bssp; Klk7; SP59; PRSS9; PRSS18
Reactivity
Human
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Kallikrein 6, Antibody; Anti-Kallikrein 6 antibody; Kallikrein-6; kallikrein-related peptidase 6; Bssp antibody; hK 6 antibody; hK6 antibody; Kallikrein 6 precursor antibody; Kallikrein related peptidase 6 antibody; Kallikrein-6 antibody; Kallikrein6 antibody; KLK 6 antibody; Klk 7 antibody; KLK 9 antibody; Klk29 antibody; Klk6 antibody; KLK6_HUMAN antibody; Klk7 antibody; KLK9 antibody; MGC9355 antibody; mGK 1 antibody; mGK1 antibody; MSP antibody; Neurosin antibody; Protease M antibody; Protease serine 18 antibody; Protease serine 9 antibody; PRSS 18 antibody; PRSS 9 antibody; PRSS18 antibody; PRSS9 antibody; Serine protease 18 antibody; Serine protease 9 antibody; SP 59 antibody; SP59 antibody; Tissue kallikrein antibody; TK antibody; Zyme antibody; anti-KLK6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
244
Applicable Applications for anti-KLK6 antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 6 (227-244aa YTNVCRYTNWIQKTIQAK).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
ICC (Immunocytochemistry)
(Anti-Kallikrein 6 antibody, AAA45162, ICCICC: PC-3 Cell)
ICC (Immunocytochemistry)
(Anti-Kallikrein 6 antibody, AAA45162, ICCICC: PC-3 Cell)
IHC (Immunohiostchemistry)
(Anti-Kallikrein 6 antibody, AAA45162, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Kallikrein 6 antibody, AAA45162, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
WB (Western Blot)
(Anti-Kallikrein 6 antibody, AAA45162, Western blottingAll lanes: Anti Kallikrein 6 (AAA45162) at 0.5ug/mlLane 1: MCF-7 Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: MM231 Whole Cell Lysate at 40ugLane 4: MM453 Whole Cell Lysate at 40ugLane 5: A549 Whole Cell Lysate at 40ugLane 6: SMMC Whole Cell Lysate at 40ugLane 7: COLO320 Whole Cell Lysate at 40ugLane 8: SW620 Whole Cell Lysate at 40ugLane 9: HT1080 Whole Cell Lysate at 40ugPredicted bind size: 27KDObserved bind size: 27KD)
WB (Western Blot)
(Anti-Kallikrein 6 antibody, AAA45162, Western blottingAll lanes: Anti Kallikrein 6 (AAA45162) at 0.5ug/mlLane 1: MCF-7 Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugLane 3: MM231 Whole Cell Lysate at 40ugLane 4: MM453 Whole Cell Lysate at 40ugLane 5: A549 Whole Cell Lysate at 40ugLane 6: SMMC Whole Cell Lysate at 40ugLane 7: COLO320 Whole Cell Lysate at 40ugLane 8: SW620 Whole Cell Lysate at 40ugLane 9: HT1080 Whole Cell Lysate at 40ugPredicted bind size: 27KDObserved bind size: 27KD)
Related Product Information for anti-KLK6 antibody
Description: Rabbit IgG polyclonal antibody for Kallikrein-6(KLK6) detection. Tested with WB, IHC-P, ICC in Human.
Background: KLK6(Kallikrein-related peptidase 6), also called KALLIKREIN 6, NEUROSIN, PROTEASE M, ZYME or PRSS9, is a protein that in humans is encoded by the KLK6 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, prostate, and ovarian cancers, but was not detected in any metastases of these cancers. The KLK6 gene is mapped on 19q13.41. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Upon cellular stress, neurosin was released from mitochondria to the cytosol, which resulted in the increase of degraded alpha-synuclein species. Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies.
Background: KLK6(Kallikrein-related peptidase 6), also called KALLIKREIN 6, NEUROSIN, PROTEASE M, ZYME or PRSS9, is a protein that in humans is encoded by the KLK6 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, prostate, and ovarian cancers, but was not detected in any metastases of these cancers. The KLK6 gene is mapped on 19q13.41. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Upon cellular stress, neurosin was released from mitochondria to the cytosol, which resulted in the increase of degraded alpha-synuclein species. Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
4,333 Da
NCBI Official Full Name
Kallikrein-6
NCBI Official Synonym Full Names
kallikrein-related peptidase 6
NCBI Official Symbol
KLK6
NCBI Official Synonym Symbols
hK6; Bssp; Klk7; SP59; PRSS9; PRSS18
NCBI Protein Information
kallikrein-6; zyme; neurosin; protease M; serine protease 9; serine protease 18
UniProt Protein Name
Kallikrein-6
UniProt Gene Name
KLK6
UniProt Synonym Gene Names
PRSS18; PRSS9
UniProt Entry Name
KLK6_HUMAN
Similar Products
Product Notes
The KLK6 klk6 (Catalog #AAA45162) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Kallikrein 6 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Kallikrein 6 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the KLK6 klk6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kallikrein 6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.