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product-image-AAA40511_IF11.jpg IF (Immunofluorescence) (Immunofluorescence of KANK1 in human kidney tissue with KANK1 antibody at 20 μg/ml.)

Rabbit anti-Human, Mouse KANK1 Polyclonal Antibody | anti-KANK1 antibody

KANK1 Antibody

Gene Names
KANK1; KANK; CPSQ2; ANKRD15
Reactivity
Human, Mouse
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
KANK1 Antibody is affinity chromatography purified via peptide column.
Synonyms
KANK1, Antibody; KANK1 Antibody; KANK1; KANK; CPSQ2; ANKRD15; KIAA0172; KN motif and ankyrin repeat domain-containing protein 1; Ankyrin repeat domain-containing protein 15; KN motif and ankyrin repeat domains 1; anti-KANK1 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Two alternatively spliced transcript variants encoding different isoforms have been identified. The lower molecular weight band seen in the immunoblot is thought to be non-specific.
Purity/Purification
KANK1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1352
Applicable Applications for anti-KANK1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
KANK1 antibody was raised against a 19 amino acid peptide near the amino terminus of human KANK1.
Buffer
KANK1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of KANK1 in human kidney tissue with KANK1 antibody at 20 μg/ml.)

product-image-AAA40511_IF11.jpg IF (Immunofluorescence) (Immunofluorescence of KANK1 in human kidney tissue with KANK1 antibody at 20 μg/ml.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of KANK1 in human kidney tissue with KANK1 antibody at 2.5 μg/ml.)

product-image-AAA40511_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of KANK1 in human kidney tissue with KANK1 antibody at 2.5 μg/ml.)

WB (Western Blot)

(Western blot analysis of KANK1 in 3T3 cell lysate with KANK1 antibody at 1 μg/mL.)

product-image-AAA40511_WB15.gif WB (Western Blot) (Western blot analysis of KANK1 in 3T3 cell lysate with KANK1 antibody at 1 μg/mL.)
Related Product Information for anti-KANK1 antibody
KANK1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 149 kDa

Observed: 150 kDa
NCBI Official Full Name
KN motif and ankyrin repeat domain-containing protein 1 isoform a
NCBI Official Synonym Full Names
KN motif and ankyrin repeat domains 1
NCBI Official Symbol
KANK1
NCBI Official Synonym Symbols
KANK; CPSQ2; ANKRD15
NCBI Protein Information
KN motif and ankyrin repeat domain-containing protein 1; kidney ankyrin repeat-containing protein; ankyrin repeat domain-containing protein 15
UniProt Protein Name
KN motif and ankyrin repeat domain-containing protein 1
UniProt Gene Name
KANK1
UniProt Synonym Gene Names
ANKRD15; KANK; KIAA0172
UniProt Entry Name
KANK1_HUMAN

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Product Notes

The KANK1 kank1 (Catalog #AAA40511) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KANK1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KANK1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the KANK1 kank1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KANK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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