Rabbit KCNK12 Polyclonal Antibody | anti-KCNK12 antibody

KCNK12 Antibody

Cat. Num. AAA39637

• Gene Names: KCNK12; THIK2; THIK-2; K2p12.1
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: KCNK12 Antibody is affinity chromatography purified via peptide column.
• Synonyms: KCNK12, Antibody; KCNK12 Antibody; KCNK12; THIK2; THIK-2; K2p12.1; Potassium channel subfamily K member 12; Tandem pore domain halothane-inhibited potassium channel 2; potassium channel, subfamily K, member 12; anti-KCNK12 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: KCNK12 antibody is predicted to not cross-react with other KCNK protein family members.
• Purity/Purification: KCNK12 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 430

• Applicable Applications for anti-KCNK12 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: KCNK12 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human KCNK12.
• Buffer: KCNK12 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: KCNK12 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of KCNK12 in mouse brain tissue with KCNK12 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of KCNK12 in mouse brain tissue with KCNK12 antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of KCNK12 in rat brain tissue lysate with KCNK12 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-KCNK12 antibody

KCNK12 Antibody: KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle. KCNK12 is closely related to KCNK13 (58% identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.

NCBI and Uniprot Product Information

• NCBI GI #: 11545761
• NCBI GeneID: 56660
• NCBI Accession #: NP_071338
• NCBI GenBank Nucleotide #: NM_022055.1
• UniProt Accession #: Q9HB15
• Molecular Weight: 46,889 Da
• NCBI Official Full Name: potassium channel subfamily K member 12
• NCBI Official Synonym Full Names: potassium channel, two pore domain subfamily K, member 12
• NCBI Official Symbol: KCNK12
• NCBI Official Synonym Symbols: THIK2; THIK-2; K2p12.1
• NCBI Protein Information: potassium channel subfamily K member 12; potassium channel, subfamily K, member 12; tandem pore domain potassium channel THIK-2; tandem pore domain halothane-inhibited potassium channel 2
• UniProt Protein Name: Potassium channel subfamily K member 12
• UniProt Gene Name: KCNK12
• UniProt Synonym Gene Names: THIK-2
• UniProt Entry Name: KCNKC_HUMAN