Rabbit KCNK13 Polyclonal Antibody | anti-KCNK13 antibody

KCNK13 Antibody

Cat. Num. AAA39703

• Gene Names: KCNK13; THIK1; THIK-1; K2p13.1
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: KCNK13 Antibody is affinity chromatography purified via peptide column.
• Synonyms: KCNK13, Antibody; KCNK13 Antibody; KCNK13; THIK1; THIK-1; K2p13.1; Potassium channel subfamily K member 13; Tandem pore domain halothane-inhibited potassium channel 1; potassium channel, subfamily K, member 13; anti-KCNK13 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: KCNK13 antibody is predicted to not cross-react with other KCNK protein family members.
• Purity/Purification: KCNK13 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 408

• Applicable Applications for anti-KCNK13 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: KCNK13 antibody was raised against a 15 amino acid synthetic peptide near the center of human KCNK13.
• Buffer: KCNK13 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: KCNK13 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of KCNK13 in human brain tissue with KCNK13 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of KCNK13 in human brain tissue with KCNK13 antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of KCNK13 in rat brain tissue lysate with KCNK13 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-KCNK13 antibody

KCNK13 Antibody: The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.

NCBI and Uniprot Product Information

• NCBI GI #: 16306555
• NCBI GeneID: 56659
• NCBI Accession #: NP_071337
• NCBI GenBank Nucleotide #: NM_022054.3
• UniProt Accession #: Q9HB14; Q96E79; B5TJL8
• Molecular Weight: 45,391 Da
• NCBI Official Full Name: potassium channel subfamily K member 13
• NCBI Official Synonym Full Names: potassium channel, two pore domain subfamily K, member 13
• NCBI Official Symbol: KCNK13
• NCBI Official Synonym Symbols: THIK1; THIK-1; K2p13.1
• NCBI Protein Information: potassium channel subfamily K member 13; K2P13.1 potassium channel; potassium channel, subfamily K, member 13; tandem pore domain potassium channel THIK-1; tandem pore domain halothane-inhibited potassium channel 1
• UniProt Protein Name: Potassium channel subfamily K member 13
• UniProt Gene Name: KCNK13
• UniProt Synonym Gene Names: THIK-1
• UniProt Entry Name: KCNKD_HUMAN