IHC (Immunohistochemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCNQ2 Antibody. The picture on the right is blocked with the synthesized peptide)
Rabbit KCNQ2 Polyclonal Antibody | anti-KCNQ2 antibody
KCNQ2 Polyclonal Antibody
Gene Names
KCNQ2; EBN; BFNC; EBN1; ENB1; HNSPC; KV7.2; KCNA11
Reactivity
Human, Mouse, Rat
Applications
ELISA, Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity Purification
Synonyms
KCNQ2, Antibody; KCNQ2 Polyclonal Antibody; anti-KCNQ2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
KCNQ2 Polyclonal Antibody detects endogenous levels of KCNQ2 protein
Purity/Purification
Affinity Purification
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Sequence Length
872
Applicable Applications for anti-KCNQ2 antibody
ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant protein of human KCNQ2 (NP_742107.1).
Conjugation
APC
Cellular Localization
Cell membrane ; Multi-pass membrane protein .
Tissue specificity
In adult and fetal brain. Highly expressed in areas containing neuronal cell bodies, low in spinal cord and corpus callosum. Isoform 2 is preferentially expressed in differentiated neurons. Isoform 6 is prominent in fetal brain, undifferentiated neuroblastoma cells and brain tumors.
Function
Alternative products:Additional isoforms seem to exist,Disease:Defects in KCNQ2 are the cause of benign neonatal epilepsy type 1 (EBN1) [MIM:121200]. Benign neonatal epilepsy is characterized by clusters of seizures occurring in the first days of life. Most patients have spontaneous remission by 12 months of age and show normal psychomotor development.The disorder is distinguished from benign familial infantile seizures by an earlier age at onset.,Disease:Defects in KCNQ2 are the cause of benign neonatal epilepsy with myokymia (EBNMK) [MIM:606437]. EBNMK is a syndrome characterized by benign neonatal convulsions followed later in life by myokymia.,Disease:Defects in KCNQ2 are the cause of myokymia isolated type 2 (MK2) [MIM:606437].
Preparation and Storage
Store at -15°C to -25°C/1 year
IHC (Immunohistochemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCNQ2 Antibody. The picture on the right is blocked with the synthesized peptide)
IHC (Immunohistochemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KCNQ2 Antibody. The picture on the right is blocked with the synthesized peptide)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
44kDa; 92kDa; 93kDa; 94kDa; 95kDa
NCBI Official Full Name
Potassium voltage-gated channel subfamily KQT member 2
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily Q member 2
NCBI Official Symbol
KCNQ2
NCBI Official Synonym Symbols
EBN; BFNC; EBN1; ENB1; HNSPC; KV7.2; KCNA11
NCBI Protein Information
potassium voltage-gated channel subfamily KQT member 2
UniProt Protein Name
Potassium voltage-gated channel subfamily KQT member 2
UniProt Gene Name
KCNQ2
UniProt Entry Name
KCNQ2_HUMAN
Similar Products
Product Notes
The KCNQ2 kcnq2 (Catalog #AAA268845) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNQ2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KCNQ2 can be used in a range of immunoassay formats including, but not limited to, ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the KCNQ2 kcnq2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNQ2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.