IHC (Immunohiostchemistry)
(KIF16b Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KIF16b Antibody for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit KIF16b Polyclonal Antibody | anti-KIF16B antibody
KIF16b Antibody
Gene Names
KIF16B; SNX23; C20orf23; KISC20ORF
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
KIF16b, Antibody; KIF16b Antibody; Kinesin-like protein KIF16B; Sorting nexin-23; KIF16B; C20orf23; KIAA1590; SNX23; anti-KIF16B antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
IgG
Specificity
This KIF16b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human KIF16b.
Purity/Purification
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
1-30
Sequence Length
1,276
Applicable Applications for anti-KIF16B antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Function
Plus end-directed microtubule-dependent motor protein involved in endosome transport and receptor recycling and degradation. Regulates the plus end motility of early endosomes and the balance between recycling and degradation of receptors such as EGF receptor (EGFR) and FGF receptor (FGFR). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.
Cellular Location
Cytoplasm, cytoskeleton. Early endosome membrane. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note: It is unclear whether association with endosomes is mediated via phosphatidylinositol 3-phosphate (PtdIns(3)P)-binding or via its interaction with RAB14.
Tissue Location
Primarily expressed in brain. Also present in kidney, liver, intestine, placenta, leukocytes, heart and skeletal muscle (at protein level).
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(KIF16b Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KIF16b Antibody for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(KIF16b Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KIF16b Antibody for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(KIF16b Antibody western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the KIF16b antibody detected the KIF16b protein (arrow).)
WB (Western Blot)
(KIF16b Antibody western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the KIF16b antibody detected the KIF16b protein (arrow).)
Related Product Information for anti-KIF16B antibody
KIF16b may be involved in several stages of intracellular trafficking. Probable microtubule-dependent motor protein (By similarity).
Product Categories/Family for anti-KIF16B antibody
References
Vasilescu, J., et al. J. Proteome Res. 6(1):298-305(2007)
Seet, L.F., et al. Biochim. Biophys. Acta 1761(8):878-896(2006)
Miki, H., et al. Trends Cell Biol. 15(9):467-476(2005)
Hoepfner, S., et al. Cell 121(3):437-450(2005)
Worby, C.A., et al. Nat. Rev. Mol. Cell Biol. 3(12):919-931(2002)
Seet, L.F., et al. Biochim. Biophys. Acta 1761(8):878-896(2006)
Miki, H., et al. Trends Cell Biol. 15(9):467-476(2005)
Hoepfner, S., et al. Cell 121(3):437-450(2005)
Worby, C.A., et al. Nat. Rev. Mol. Cell Biol. 3(12):919-931(2002)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated MW: 152011
NCBI Official Full Name
kinesin-like protein KIF16B isoform 3
NCBI Official Synonym Full Names
kinesin family member 16B
NCBI Official Symbol
KIF16B
NCBI Official Synonym Symbols
SNX23; C20orf23; KISC20ORF
NCBI Protein Information
kinesin-like protein KIF16B
UniProt Protein Name
Kinesin-like protein KIF16B
UniProt Gene Name
KIF16B
UniProt Synonym Gene Names
C20orf23; KIAA1590; SNX23
UniProt Entry Name
KI16B_HUMAN
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Product Notes
The KIF16B kif16b (Catalog #AAA285031) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The KIF16b Antibody reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's KIF16b can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the KIF16B kif16b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KIF16b, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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