WB (Western Blot)
(KLHL12 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the KLHL12 antibody detected the KLHL12 protein (arrow).)
Rabbit KLHL12 Polyclonal Antibody | anti-KLHL12 antibody
KLHL12 Antibody (C-term)
Gene Names
KLHL12; DKIR; C3IP1
Reactivity
Human, mouse (Predicted Reactivity: Bovine, Zebrafish, Rat, Xenopus)
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
KLHL12, Antibody; KLHL12 Antibody (C-term); Kelch-like protein 12; CUL3-interacting protein 1; DKIR homolog; hDKIR; KLHL12; C3IP1; anti-KLHL12 antibody
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Bovine, Zebrafish, Rat, Xenopus)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This KLHL12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-404 amino acids from the C-terminal region of human KLHL12.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.41 (varies by lot)
Sequence Positions
376-404
Sequence Length
568
Applicable Applications for anti-KLHL12 antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(KLHL12 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the KLHL12 antibody detected the KLHL12 protein (arrow).)
WB (Western Blot)
(KLHL12 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the KLHL12 antibody detected the KLHL12 protein (arrow).)
WB (Western Blot)
(KLHL12 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the KLHL12 antibody detected the KLHL12 protein (arrow).)
WB (Western Blot)
(KLHL12 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the KLHL12 antibody detected the KLHL12 protein (arrow).)
Related Product Information for anti-KLHL12 antibody
Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
References
Ehret, G.B., et al. Eur. J. Hum. Genet. 17(12):1650-1657(2009)
Rondou, P., et al. J. Biol. Chem. 283(17):11083-11096(2008)
Lim, J., et al. Cell 125(4):801-814(2006)
Angers, S., et al. Nat. Cell Biol. 8(4):348-357(2006)
Uchida, K., et al. Immunology 116(1):53-63(2005)
Rondou, P., et al. J. Biol. Chem. 283(17):11083-11096(2008)
Lim, J., et al. Cell 125(4):801-814(2006)
Angers, S., et al. Nat. Cell Biol. 8(4):348-357(2006)
Uchida, K., et al. Immunology 116(1):53-63(2005)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63277
NCBI Official Full Name
kelch-like protein 12 isoform 2
NCBI Official Synonym Full Names
kelch-like family member 12
NCBI Official Symbol
KLHL12
NCBI Official Synonym Symbols
DKIR; C3IP1
NCBI Protein Information
kelch-like protein 12
UniProt Protein Name
Kelch-like protein 12
UniProt Gene Name
KLHL12
UniProt Synonym Gene Names
C3IP1; hDKIR
UniProt Entry Name
KLH12_HUMAN
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Product Notes
The KLHL12 klhl12 (Catalog #AAA283741) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 376-404. The KLHL12 Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Bovine, Zebrafish, Rat, Xenopus) and may cross-react with other species as described in the data sheet. AAA Biotech's KLHL12 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the KLHL12 klhl12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLHL12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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