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IHC (Immunohistochemistry)
(Immunohistochemistry of KLOTHO in rat heart tissue with KLOTHO antibody at 2.5 μg/ml.)
Rabbit KLOTHO Polyclonal Antibody | anti-KL antibody
KLOTHO Antibody
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
KLOTHO Antibody is affinity chromatography purified via peptide column.
Synonyms
KLOTHO, Antibody; KLOTHO Antibody; KLOTHO; Klotho; klotho; anti-KL antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Three isoforms of KLOTHO are known to exist.
Purity/Purification
KLOTHO Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1012
Applicable Applications for anti-KL antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
KLOTHO antibody was raised against a 16 amino acid synthetic peptide near the center of human KLOTHO.
Buffer
KLOTHO Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
KLOTHO antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohistochemistry)
(Immunohistochemistry of KLOTHO in rat heart tissue with KLOTHO antibody at 2.5 μg/ml.)
IHC (Immunohistochemistry)
(Immunohistochemistry of KLOTHO in rat heart tissue with KLOTHO antibody at 2.5 μg/ml.)
IF (Immunofluorescence)
(Immunofluorescence of KLOTHO in mouse heart tissue with KLOTHO antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of KLOTHO in mouse heart tissue with KLOTHO antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of KLOTHO in mouse heart tissue with KLOTHO antibody at 2.5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of KLOTHO in mouse heart tissue with KLOTHO antibody at 2.5 μg/mL.)
WB (Western Blot)
(Western blot analysis of KLOTHO in HepG2 cell lysate with KLOTHO antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of KLOTHO in HepG2 cell lysate with KLOTHO antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-KL antibody
KLOTHO Antibody: KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 111 kDa
Observed: 106 kDa
Observed: 106 kDa
NCBI Official Full Name
klotho
NCBI Official Synonym Full Names
klotho
NCBI Official Symbol
KL
NCBI Protein Information
klotho
UniProt Protein Name
Klotho
UniProt Gene Name
KL
UniProt Entry Name
KLOT_HUMAN
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Product Notes
The KL kl (Catalog #AAA39442) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLOTHO Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's KLOTHO can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the KL kl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLOTHO, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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