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product-image-AAA230885_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue using AAA230885 at dilution 1:100)

Rabbit anti-Human KPNA6 Polyclonal Antibody | anti-KPNA6 antibody

KPNA6 Antibody

Gene Names
KPNA6; IPOA7; KPNA7
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
KPNA6, Antibody; KPNA6 Antibody; Importin subunit alpha-7; Karyopherin subunit alpha-6; KPNA6; IPOA7; anti-KPNA6 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
536
Applicable Applications for anti-KPNA6 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Species
Human
Immunogen
Recombinant human Importin subunit alpha-7 protein (C-260AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-68197
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using AAA230885 at dilution 1:100)

product-image-AAA230885_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue using AAA230885 at dilution 1:100)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human prostate cancer using AAA230885 at dilution 1:100)

product-image-AAA230885_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human prostate cancer using AAA230885 at dilution 1:100)

WB (Western Blot)

(Western blotAll lanes: KPNA6 antibody at 0.95ug/mlLane 1 : PC-3 whole cell lysateLane 2 : Hela whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 60 kDaObserved band size: 60 kDa)

product-image-AAA230885_WB15.jpg WB (Western Blot) (Western blotAll lanes: KPNA6 antibody at 0.95ug/mlLane 1 : PC-3 whole cell lysateLane 2 : Hela whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 60 kDaObserved band size: 60 kDa)
Related Product Information for anti-KPNA6 antibody
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60,030 Da
NCBI Official Full Name
importin subunit alpha-7
NCBI Official Synonym Full Names
karyopherin subunit alpha 6
NCBI Official Symbol
KPNA6
NCBI Official Synonym Symbols
IPOA7; KPNA7
NCBI Protein Information
importin subunit alpha-7
UniProt Protein Name
Importin subunit alpha-7
UniProt Gene Name
KPNA6
UniProt Synonym Gene Names
IPOA7
UniProt Entry Name
IMA7_HUMAN

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Product Notes

The KPNA6 kpna6 (Catalog #AAA230885) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KPNA6 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KPNA6 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the KPNA6 kpna6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KPNA6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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