ICC (Immunocytochemistry)
(Immunocytochemistry of KREMEN2 in HeLa cells with KREMEN2 antibody at 5 μg/ml.)
Rabbit anti-Human, Mouse KREMEN2 Polyclonal Antibody | anti-KREMEN2 antibody
KREMEN2 Antibody
Gene Names
KREMEN2; KRM2
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
KREMEN2 Antibody is affinity chromatography purified via peptide column.
Synonyms
KREMEN2, Antibody; KREMEN2 Antibody; KREMEN2; KRM2; Kremen protein 2; Dickkopf receptor 2; kringle containing transmembrane protein 2; anti-KREMEN2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Multiple isoforms of KREMEN2 are known to exist. KREMEN2 antibody is predicted to not cross-react with other Kremen protein family members.
Purity/Purification
KREMEN2 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
462
Applicable Applications for anti-KREMEN2 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
KREMEN2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human KREMEN2.
Buffer
KREMEN2 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
KREMEN2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
ICC (Immunocytochemistry)
(Immunocytochemistry of KREMEN2 in HeLa cells with KREMEN2 antibody at 5 μg/ml.)
ICC (Immunocytochemistry)
(Immunocytochemistry of KREMEN2 in HeLa cells with KREMEN2 antibody at 5 μg/ml.)
WB (Western Blot)
(Western blot analysis of KREMEN2 in HeLa cell lysate with KREMEN2 antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of KREMEN2 in HeLa cell lysate with KREMEN2 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-KREMEN2 antibody
KREMEN2 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) co-receptor. Recent experiments have shown that KREMEN2 is a regulator of bone remodeling and raise the possibility that antagonizing KREMEN2 might prove beneficial in patients with bone loss disorders.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 51 kDa
Observed: 54 kDa
Observed: 54 kDa
NCBI Official Full Name
kremen protein 2 isoform d
NCBI Official Synonym Full Names
kringle containing transmembrane protein 2
NCBI Official Symbol
KREMEN2
NCBI Official Synonym Symbols
KRM2
NCBI Protein Information
kremen protein 2; dickkopf receptor 2; kringle domain-containing transmembrane protein 2; kringle-containing protein marking the eye and the nose
UniProt Protein Name
Kremen protein 2
UniProt Gene Name
KREMEN2
UniProt Synonym Gene Names
KRM2
UniProt Entry Name
KREM2_HUMAN
Similar Products
Product Notes
The KREMEN2 kremen2 (Catalog #AAA40659) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KREMEN2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KREMEN2 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the KREMEN2 kremen2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KREMEN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.