IP (Immunoprecipitation)
(Immunoprecipitation of Ku80 in either CHO or A549 nuclear extracts (NE) or cytoplasmic lysates (cyto). A Ku80 deficient cell lysate, XRS, was used as a negative control.)
Rabbit Ku80 Polyclonal Antibody | anti-XRCC5 antibody
Anti-Ku80 Antibody
Gene Names
XRCC5; KU80; KUB2; Ku86; NFIV; KARP1; KARP-1
Reactivity
Hamster, Human, Mouse, Rat
Applications
Western Blot
Synonyms
Ku80, Antibody; Anti-Ku80 Antibody; XRCC5; X-ray repair cross-complementing protein 5; ATP-dependent DNA helicase 2 subunit 2; Ku86; CTC box-binding factor 85 kDa subunit; Lupus Ku autoantigen protein p86; Thyroid-lupus autoantigen; TLAA; G22P2; Ku80; anti-XRCC5 antibody
Host
Rabbit
Reactivity
Hamster, Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Reacts with the 80 kDa Ku80 protein. Sequence is 100% conserved between human, mouse, rat and hamster.
Form/Format
Liquid; Antigen Affinity Purified; PBS + 0.02% NaN3
Applicable Applications for anti-XRCC5 antibody
WB (Western Blot)
Immunogen Species
Human
Immunogen
Synthetic peptide corresponding to amino acids from an internal sequence of the human Ku80 protein
Country of Origin
United States
Preparation and Storage
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20 degree C or -80 degree C, while keeping a working aliquot stored at 4 degree C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
After date of receipt, stable for at least 1 year at -20 degree C.
After date of receipt, stable for at least 1 year at -20 degree C.
IP (Immunoprecipitation)
(Immunoprecipitation of Ku80 in either CHO or A549 nuclear extracts (NE) or cytoplasmic lysates (cyto). A Ku80 deficient cell lysate, XRS, was used as a negative control.)
IP (Immunoprecipitation)
(Immunoprecipitation of Ku80 in either CHO or A549 nuclear extracts (NE) or cytoplasmic lysates (cyto). A Ku80 deficient cell lysate, XRS, was used as a negative control.)
Related Product Information for anti-XRCC5 antibody
Ku80 rabbit polyclonal primary antibody from the lab is produced in-house. It detects hamster, human, mouse, and rat Ku80 and is antigen affinity purified. It is great for use in WB.
Telomere length maintenance, an activity essential for chromosome stability and genome integrity, is regulated by telomerase- and telomere-associated factors. The DNA repair protein Ku (a heterodimer of Ku70 and Ku80 subunits) associates with mammalian telomeres and contributes to telomere maintenance. The Ku heterodimer functions at two kinds of DNA ends: telomeres and double-strand breaks. The role that Ku plays at these two classes of termini must be distinct, because Ku is required for accurate and efficient joining of double-strand breaks while similar DNA repair events are normally prohibited at chromosome ends
Telomere length maintenance, an activity essential for chromosome stability and genome integrity, is regulated by telomerase- and telomere-associated factors. The DNA repair protein Ku (a heterodimer of Ku70 and Ku80 subunits) associates with mammalian telomeres and contributes to telomere maintenance. The Ku heterodimer functions at two kinds of DNA ends: telomeres and double-strand breaks. The role that Ku plays at these two classes of termini must be distinct, because Ku is required for accurate and efficient joining of double-strand breaks while similar DNA repair events are normally prohibited at chromosome ends
Product Categories/Family for anti-XRCC5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
82,705 Da
NCBI Official Full Name
X-ray repair cross-complementing protein 5
NCBI Official Synonym Full Names
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
NCBI Official Symbol
XRCC5
NCBI Official Synonym Symbols
KU80; KUB2; Ku86; NFIV; KARP1; KARP-1
NCBI Protein Information
X-ray repair cross-complementing protein 5; TLAA; CTC85; CTCBF; nuclear factor IV; Ku autoantigen, 80kDa; DNA repair protein XRCC5; thyroid-lupus autoantigen; 86 kDa subunit of Ku antigen; lupus Ku autoantigen protein p86; Ku86 autoantigen related protein
UniProt Protein Name
X-ray repair cross-complementing protein 5
UniProt Gene Name
XRCC5
UniProt Synonym Gene Names
G22P2; CTC85; CTCBF; TLAA
UniProt Entry Name
XRCC5_HUMAN
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Product Notes
The XRCC5 xrcc5 (Catalog #AAA72770) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Ku80 Antibody reacts with Hamster, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Ku80 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the XRCC5 xrcc5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ku80, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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