WB (Western Blot)
(L1CAM Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the L1CAM antibody detected the L1CAM protein (arrow).)
Rabbit L1CAM Polyclonal Antibody | anti-L1CAM antibody
L1CAM Antibody (C-term)
Gene Names
L1CAM; S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1
Reactivity
Human, mouse (Predicted Reactivity: Rat)
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
L1CAM, Antibody; L1CAM Antibody (C-term); Neural cell adhesion molecule L1; N-CAM-L1; NCAM-L1; CD171; L1CAM; CAML1; MIC5; anti-L1CAM antibody
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This L1CAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1154-1182 amino acids from the C-terminal region of human L1CAM.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
1154-1182
Sequence Length
1257
Applicable Applications for anti-L1CAM antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(L1CAM Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the L1CAM antibody detected the L1CAM protein (arrow).)
WB (Western Blot)
(L1CAM Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the L1CAM antibody detected the L1CAM protein (arrow).)
WB (Western Blot)
(L1CAM Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the L1CAM antibody detected the L1CAM protein (arrow).)
WB (Western Blot)
(L1CAM Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the L1CAM antibody detected the L1CAM protein (arrow).)
Related Product Information for anti-L1CAM antibody
L1CAM is an axonal glycoprotein
belonging to the immunoglobulin supergene family. The ectodomain,
consisting of several immunoglobulin-like domains and
fibronectin-like repeats (type III), is linked via a single
transmembrane sequence to a conserved cytoplasmic domain. This cell
adhesion molecule plays an important role in nervous system
development, including neuronal migration and differentiation.
Mutations in the gene cause three X-linked neurological syndromes
known by the acronym CRASH (corpus callosum hypoplasia,
retardation, aphasia, spastic paraplegia and hydrocephalus).
Alternative splicing of a neuron-specific exon is thought to be
functionally relevant.
belonging to the immunoglobulin supergene family. The ectodomain,
consisting of several immunoglobulin-like domains and
fibronectin-like repeats (type III), is linked via a single
transmembrane sequence to a conserved cytoplasmic domain. This cell
adhesion molecule plays an important role in nervous system
development, including neuronal migration and differentiation.
Mutations in the gene cause three X-linked neurological syndromes
known by the acronym CRASH (corpus callosum hypoplasia,
retardation, aphasia, spastic paraplegia and hydrocephalus).
Alternative splicing of a neuron-specific exon is thought to be
functionally relevant.
Product Categories/Family for anti-L1CAM antibody
References
Schafer, M.K., et al. FEBS Lett. 584(21):4475-4480(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Bertolin, C., et al. J. Neurol. Sci. 294 (1-2), 124-126 (2010) :
Schafer, M.K., et al. Cell. Mol. Life Sci. 67(14):2425-2437(2010)
Gavert, N., et al. J. Cell. Sci. 123 (PT 12), 2135-2143 (2010) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Bertolin, C., et al. J. Neurol. Sci. 294 (1-2), 124-126 (2010) :
Schafer, M.K., et al. Cell. Mol. Life Sci. 67(14):2425-2437(2010)
Gavert, N., et al. J. Cell. Sci. 123 (PT 12), 2135-2143 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
140003
NCBI Official Full Name
neural cell adhesion molecule L1 isoform 1
NCBI Official Synonym Full Names
L1 cell adhesion molecule
NCBI Official Symbol
L1CAM
NCBI Official Synonym Symbols
S10; HSAS; MASA; MIC5; SPG1; CAML1; CD171; HSAS1; N-CAML1; NCAM-L1; N-CAM-L1
NCBI Protein Information
neural cell adhesion molecule L1
UniProt Protein Name
Neural cell adhesion molecule L1
UniProt Gene Name
L1CAM
UniProt Synonym Gene Names
CAML1; MIC5; N-CAM-L1; NCAM-L1
UniProt Entry Name
L1CAM_HUMAN
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Product Notes
The L1CAM l1cam (Catalog #AAA287961) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1154-1182. The L1CAM Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's L1CAM can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the L1CAM l1cam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "L1CAM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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