IF (Immunofluorescence)
(Immunofluorescence analysis of L929 cells using Laminin beta 1 Polyclonal Antibody.)
Rabbit anti-Human, Mouse LAMB1 Polyclonal Antibody | anti-LAMB1 antibody
LAMB1 Rabbit Polyclonal Antibody
Gene Names
LAMB1; CLM; LIS5
Reactivity
Human, Mouse
Applications
Immunofluorescence, Western Blot
Purity
Affinity purification
Synonyms
LAMB1, Antibody; LAMB1 Rabbit Polyclonal Antibody; LAMB1; CLM; LIS5; anti-LAMB1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Applicable Applications for anti-LAMB1 antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen
Recombinant fusion protein of human Laminin beta 1 (NP_002282.2).
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of L929 cells using Laminin beta 1 Polyclonal Antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of L929 cells using Laminin beta 1 Polyclonal Antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using Laminin beta 1 antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using Laminin beta 1 antibody.)
Related Product Information for anti-LAMB1 antibody
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. This gene encodes the beta chain isoform laminin, beta 1. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis.
Product Categories/Family for anti-LAMB1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
198,038 Da
NCBI Official Full Name
laminin subunit beta-1
NCBI Official Synonym Full Names
laminin, beta 1
NCBI Official Symbol
LAMB1
NCBI Official Synonym Symbols
CLM; LIS5
NCBI Protein Information
laminin subunit beta-1; laminin B1 chain
UniProt Protein Name
Laminin subunit beta-1
UniProt Gene Name
LAMB1
UniProt Entry Name
LAMB1_HUMAN
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Product Notes
The LAMB1 lamb1 (Catalog #AAA314210) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LAMB1 Rabbit Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LAMB1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the LAMB1 lamb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LAMB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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