IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using LGI1 antibody at 2.5 ug/mL.)
Rabbit LGI1 Polyclonal Antibody | anti-LGI1 antibody
LGI1 Antibody
Gene Names
LGI1; EPT; ETL1; ADLTE; ADPAEF; ADPEAF; IB1099; EPITEMPIN
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
LGI1, Antibody; LGI1 Antibody; Leucine-rich, glioma inactivated 1, epitempin, EPT; anti-LGI1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
This LGI1 antibody is predicted to be specific to LGI1 and not recognize other LGI proteins.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
557
Applicable Applications for anti-LGI1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 14 amino acid peptide from near the center of human LGI1.
Target Name
LGI1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using LGI1 antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using LGI1 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of LGI1 in HeLa cell lysate with LGI1 antibody at 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of LGI1 in HeLa cell lysate with LGI1 antibody at 2 ug/mL.)
Related Product Information for anti-LGI1 antibody
The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist; this LGI1 antibody will recognize only the longer form.
Product Categories/Family for anti-LGI1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
58,302 Da
NCBI Official Full Name
LGI1
NCBI Official Synonym Full Names
leucine-rich, glioma inactivated 1
NCBI Official Symbol
LGI1
NCBI Official Synonym Symbols
EPT; ETL1; ADLTE; ADPAEF; ADPEAF; IB1099; EPITEMPIN
NCBI Protein Information
leucine-rich glioma-inactivated protein 1
UniProt Protein Name
Leucine-rich glioma-inactivated protein 1
UniProt Gene Name
LGI1
UniProt Synonym Gene Names
EPT
UniProt Entry Name
LGI1_HUMAN
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Product Notes
The LGI1 lgi1 (Catalog #AAA304265) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LGI1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's LGI1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the LGI1 lgi1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LGI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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