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product-image-AAA118909_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human kidney using AAA118909 at dilution 1:100)

Rabbit anti-Human Low-density lipoprotein receptor-related protein 6 Polyclonal Antibody | anti-LRP6 antibody

Rabbit anti-human Low-density lipoprotein receptor-related protein 6 polyclonal Antibody(LRP6)

Gene Names
LRP6; ADCAD2
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purified
Synonyms
Low-density lipoprotein receptor-related protein 6, Antibody; Rabbit anti-human Low-density lipoprotein receptor-related protein 6 polyclonal Antibody(LRP6); LRP-6; LRP6; anti-LRP6 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
1613
Applicable Applications for anti-LRP6 antibody
IHC (Immunohistochemistry), ELISA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Low-density lipoprotein receptor-related protein 6 protein (20-150aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-17982 / sc-17984 / sc-134462 / sc-15399
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human kidney using AAA118909 at dilution 1:100)

product-image-AAA118909_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human kidney using AAA118909 at dilution 1:100)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human breast cancer using AAA118909 at dilution 1:100)

product-image-AAA118909_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded human breast cancer using AAA118909 at dilution 1:100)
Related Product Information for anti-LRP6 antibody
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
180,429 Da
NCBI Official Full Name
low-density lipoprotein receptor-related protein 6
NCBI Official Synonym Full Names
LDL receptor related protein 6
NCBI Official Symbol
LRP6
NCBI Official Synonym Symbols
ADCAD2
NCBI Protein Information
low-density lipoprotein receptor-related protein 6
UniProt Protein Name
Low-density lipoprotein receptor-related protein 6
UniProt Gene Name
LRP6
UniProt Synonym Gene Names
LRP-6
UniProt Entry Name
LRP6_HUMAN

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Product Notes

The LRP6 lrp6 (Catalog #AAA118909) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Low-density lipoprotein receptor-related protein 6 polyclonal Antibody(LRP6) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Low-density lipoprotein receptor-related protein 6 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the LRP6 lrp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Low-density lipoprotein receptor-related protein 6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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