IHC (Immunohiostchemistry)
(Anti- LOXL1 Picoband antibody, AAA46502, IHC(P)IHC(P): Human Prostatic Cancer Tissue)
anti-Human LOXL1 Polyclonal Antibody | anti-LOXL1 antibody
Anti-LOXL1 Antibody
Gene Names
LOXL1; LOL; LOXL
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen Affinity Purified
Synonyms
LOXL1, Antibody; Anti-LOXL1 Antibody; Lysyl oxidase homolog 1; Lysyl oxidase like 1; LOL; LOXL; Lysyl oxidase like protein 1; lysyl oxidase-like 1; anti-LOXL1 antibody
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
574
Applicable Applications for anti-LOXL1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL1 (397-425aa AEEKCLASTAYAPEATDYDVRVLLRFPQR), different from the related mouse sequence by one amino acid.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti- LOXL1 Picoband antibody, AAA46502, IHC(P)IHC(P): Human Prostatic Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti- LOXL1 Picoband antibody, AAA46502, IHC(P)IHC(P): Human Prostatic Cancer Tissue)
WB (Western Blot)
(Anti- LOXL1 Picoband antibody, AAA46502, Western blottingAll lanes: Anti LOXL1 (AAA46502) at 0.5ug/mlLane 1: A549 Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 63KDObserved bind size: 63KD)
WB (Western Blot)
(Anti- LOXL1 Picoband antibody, AAA46502, Western blottingAll lanes: Anti LOXL1 (AAA46502) at 0.5ug/mlLane 1: A549 Whole Cell Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 63KDObserved bind size: 63KD)
Related Product Information for anti-LOXL1 antibody
Description: Rabbit IgG polyclonal antibody for Lysyl oxidase homolog 1(LOXL1) detection. Tested with WB, IHC-P in Human.
Background: Lysyl oxidase homolog 1, also known as LOXL1, is an enzyme which in humans is encoded by the LOXL1 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Background: Lysyl oxidase homolog 1, also known as LOXL1, is an enzyme which in humans is encoded by the LOXL1 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
References
1. Kenyon K, Modi WS, Contente S, Friedman RM (September 1993). "A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25". The Journal of Biological Chemistry 268 (25): 18435-7. 2. Liu X, Zhao Y, Gao J, Pawlyk B, Starcher B, Spencer JA, Yanagisawa H, Zuo J, Li T (Feb 2004). "Elastic fiber homeostasis requires lysyl oxidase-like 1 protein". Nat. Genet. (United States) 36 (2): 178-82. 3. "Entrez Gene: LOXL1 lysyl oxidase-like 1".
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63,110 Da
NCBI Official Full Name
lysyl oxidase homolog 1 preproprotein
NCBI Official Synonym Full Names
lysyl oxidase like 1
NCBI Official Symbol
LOXL1
NCBI Official Synonym Symbols
LOL; LOXL
NCBI Protein Information
lysyl oxidase homolog 1
UniProt Protein Name
Lysyl oxidase homolog 1
UniProt Gene Name
LOXL1
UniProt Synonym Gene Names
LOXL; LOL
UniProt Entry Name
LOXL1_HUMAN
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Product Notes
The LOXL1 loxl1 (Catalog #AAA46502) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-LOXL1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LOXL1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the LOXL1 loxl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LOXL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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