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product-image-AAA51662_IHC10.jpg IHC (Immunohistochemistry) (Anti-LPHN2 / Latrophilin-2 antibody IHC of human prostate, carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit LPHN2 / Latrophilin-2 Polyclonal Antibody | anti-LPHN2 antibody

Rabbit Polyclonal to Human LPHN2 / Latrophilin-2

Gene Names
LPHN2; CL2; LEC1; CIRL2; LPHH1
Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Monkey, Mouse, Rat, Horse, Rabbit (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
LPHN2 / Latrophilin-2, Antibody; Rabbit Polyclonal to Human LPHN2 / Latrophilin-2; Anti-LPHN2 / Latrophilin-2 Antibody (C-Terminus) IHC-plus; LPHN2; Cl2aa; CIRL2; CL2; Latrophilin 1; Latrophilin-2; Lectomedin-1; Latrophilin 2; Latrophilin homolog 2 (cow); KIAA0786; Beta-latrotoxin receptor; CIRL-2; Latrophilin homolog 1; Latrotoxin receptor 2; Latrotoxin receptor homolog 2; LEC1; LPHH1; Human LPHN2; anti-LPHN2 antibody
Ordering
Host
Rabbit
Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Monkey, Mouse, Rat, Horse, Rabbit (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human LPHN2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
1403
Applicable Applications for anti-LPHN2 antibody
IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from C-terminus of human LPHN2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Mouse, Rat, Elephant, Horse, Rabbit, Opossum, Turkey, Platypus (94%).
Immunogen Type
Synthetic peptide
Immunogen
LPHN2 / Latrophilin-2 antibody was raised against synthetic 16 amino acid peptide from C-terminus of human LPHN2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Mouse, Rat, Elephant, Horse, Rabbit, Opossum, Turkey, Platypus (94%); Bat, Bovine, Hamster, Panda, Pig, Xenopus (88%); Dog (81%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

IHC (Immunohistochemistry)

(Anti-LPHN2 / Latrophilin-2 antibody IHC of human prostate, carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

product-image-AAA51662_IHC10.jpg IHC (Immunohistochemistry) (Anti-LPHN2 / Latrophilin-2 antibody IHC of human prostate, carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

IHC (Immunohistochemisry)

(Anti-LPHN2 / Latrophilin-2 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

product-image-AAA51662_IHC11.jpg IHC (Immunohistochemisry) (Anti-LPHN2 / Latrophilin-2 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

IHC (Immunohiostchemistry)

(Anti-LPHN2 / Latrophilin-2 antibody IHC of human prostate, smooth muscle, benign prostatic hyperplasia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

product-image-AAA51662_IHC13.jpg IHC (Immunohiostchemistry) (Anti-LPHN2 / Latrophilin-2 antibody IHC of human prostate, smooth muscle, benign prostatic hyperplasia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

IHC (Immunohistochemistry)

(Anti-LPHN2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

product-image-AAA51662_IHC15.jpg IHC (Immunohistochemistry) (Anti-LPHN2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-LPHN2 antibody
Latrophilin-2 is an Orphan-B Receptor that binds alpha-latrotoxin, a potent presynaptic neurotoxin present in the venom of the black widow spider, in a Ca2+-independent manner. As with the other two latrophilins, it shares homology with lectin, olfactomedin, and transmembrane domains, and possesses variable C-termini and various alternative-splice sites. Latrophilin-2 is endoproteolytically cleaved at the end of the GPS domain, and the two subunits remain non-covalently linked as a heterodimer.
Product Categories/Family for anti-LPHN2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
163,448 Da
NCBI Official Full Name
latrophilin-2 isoform 1 preproprotein
NCBI Official Synonym Full Names
latrophilin 2
NCBI Official Symbol
LPHN2
NCBI Official Synonym Symbols
CL2; LEC1; CIRL2; LPHH1
NCBI Protein Information
latrophilin-2; lectomedin-1; latrophilin homolog 1; calcium-independent alpha-latrotoxin receptor 2
UniProt Protein Name
Latrophilin-2
UniProt Gene Name
LPHN2
UniProt Synonym Gene Names
KIAA0786; LEC1; LPHH1; CIRL-2
UniProt Entry Name
LPHN2_HUMAN

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Product Notes

The LPHN2 lphn2 (Catalog #AAA51662) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human LPHN2 / Latrophilin-2 reacts with Gibbon, Gorilla, Human Predicted Reactivity: Monkey, Mouse, Rat, Horse, Rabbit (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's LPHN2 / Latrophilin-2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the LPHN2 lphn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LPHN2 / Latrophilin-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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