WB (Western Blot)
(LRCH1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LRCH1 antibody detected the LRCH1 protein (arrow).)
Rabbit LRCH1 Polyclonal Antibody | anti-LRCH1 antibody
LRCH1 Antibody (Center)
Gene Names
LRCH1; NP81; CHDC1
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
ELISA, Western Blot
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Synonyms
LRCH1, Antibody; LRCH1 Antibody (Center); Leucine-rich repeat and calponin homology domain-containing protein 1; Calponin homology domain-containing protein 1; Neuronal protein 81; NP81; LRCH1; CHDC1; KIAA1016; anti-LRCH1 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This LRCH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-333 amino acids from the Central region of human LRCH1.
Purity/Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Positions
304-333
Applicable Applications for anti-LRCH1 antibody
ELISA, WB (Western Blot)
Clone Names
RB42699
Function
Acts as a negative regulator of GTPase CDC42 by sequestering CDC42-guanine exchange factor DOCK8. Probably by preventing CDC42 activation, negatively regulates CD4(+) T-cell migration.
Cellular Location
Cytoplasm.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(LRCH1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LRCH1 antibody detected the LRCH1 protein (arrow).)
WB (Western Blot)
(LRCH1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the LRCH1 antibody detected the LRCH1 protein (arrow).)
Related Product Information for anti-LRCH1 antibody
This gene encodes a protein with a leucine-rich repeat and
a calponin homology domain. Polymorphism in this gene may be
associated with susceptibililty to knee osteoarthritis. Alternative
splicing results in multiple transcript variants encoding different
isoforms.
a calponin homology domain. Polymorphism in this gene may be
associated with susceptibililty to knee osteoarthritis. Alternative
splicing results in multiple transcript variants encoding different
isoforms.
Product Categories/Family for anti-LRCH1 antibody
References
Zintzaras, E., et al. Am. J. Epidemiol. 171(8):851-858(2010)
Jiang, Q., et al. J. Hum. Genet. 53(1):42-47(2008)
Ikegawa, S. Curr Opin Rheumatol 19(5):429-434(2007)
Snelling, S., et al. Rheumatology (Oxford) 46(2):250-252(2007)
Spector, T.D., et al. Arthritis Rheum. 54(2):524-532(2006)
Jiang, Q., et al. J. Hum. Genet. 53(1):42-47(2008)
Ikegawa, S. Curr Opin Rheumatol 19(5):429-434(2007)
Snelling, S., et al. Rheumatology (Oxford) 46(2):250-252(2007)
Spector, T.D., et al. Arthritis Rheum. 54(2):524-532(2006)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80875
NCBI Official Full Name
leucine-rich repeat and calponin homology domain-containing protein 1 isoform 1
NCBI Official Synonym Full Names
leucine-rich repeats and calponin homology (CH) domain containing 1
NCBI Official Symbol
LRCH1
NCBI Official Synonym Symbols
NP81; CHDC1
NCBI Protein Information
leucine-rich repeat and calponin homology domain-containing protein 1
UniProt Protein Name
Leucine-rich repeat and calponin homology domain-containing protein 1
UniProt Gene Name
LRCH1
UniProt Synonym Gene Names
CHDC1; KIAA1016; NP81
UniProt Entry Name
LRCH1_HUMAN
Similar Products
Product Notes
The LRCH1 lrch1 (Catalog #AAA290195) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 304-333. The LRCH1 Antibody (Center) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's LRCH1 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the LRCH1 lrch1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRCH1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.