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product-image-AAA231321_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human pancreatic cancer AAA231321 at dilution 1:100)

Rabbit anti-Human LRP4 Polyclonal Antibody | anti-LRP4 antibody

LRP4 Antibody

Gene Names
LRP4; CLSS; CMS17; LRP-4; LRP10; MEGF7; SOST2
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purified
Synonyms
LRP4, Antibody; LRP4 Antibody; Low-density lipoprotein receptor-related protein 4; LRP-4; Multiple epidermal growth factor-like domains 7; LRP4; KIAA0816; LRP10; MEGF7; anti-LRP4 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
1905
Applicable Applications for anti-LRP4 antibody
IHC (Immunohistochemistry), ELISA
Species
Human
Immunogen
Recombinant human Low-density lipoprotein receptor-related protein 4 protein (1500-1725AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-98775
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human pancreatic cancer AAA231321 at dilution 1:100)

product-image-AAA231321_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human pancreatic cancer AAA231321 at dilution 1:100)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human adrenal gland tissue AAA231321 at dilution 1:100)

product-image-AAA231321_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue AAA231321 at dilution 1:100)
Related Product Information for anti-LRP4 antibody
Mediates SOST-dependent inhibition of bone formation. Functions as a specific facilitator of SOST-mediated inhibition of Wnt signaling. Plays a key role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Directly binds AGRIN and recruits it to the MUSK signaling complex. Mediates the AGRIN-induced phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Alternatively, may be involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway. More generally, has been proposed to function as a cell surface endocytic receptor binding and internalizing extracellular ligands for degradation by lysosomes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
212,045 Da
NCBI Official Full Name
low-density lipoprotein receptor-related protein 4
NCBI Official Synonym Full Names
LDL receptor related protein 4
NCBI Official Symbol
LRP4
NCBI Official Synonym Symbols
CLSS; CMS17; LRP-4; LRP10; MEGF7; SOST2
NCBI Protein Information
low-density lipoprotein receptor-related protein 4
UniProt Protein Name
Low-density lipoprotein receptor-related protein 4
UniProt Gene Name
LRP4
UniProt Synonym Gene Names
KIAA0816; LRP10; MEGF7; LRP-4
UniProt Entry Name
LRP4_HUMAN

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Product Notes

The LRP4 lrp4 (Catalog #AAA231321) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LRP4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRP4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the LRP4 lrp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LRP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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