IHC (Immunohistochemisry)
(Immunofluorescent analysis of HepG2 cells using AAA119674 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Rabbit anti-Human LRRC8E Polyclonal Antibody | anti-LRRC8E antibody
LRRC8E Antibody
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, ELISA
Purity
>95%, Protein G Purified
Synonyms
LRRC8E, Antibody; LRRC8E Antibody; Volume-regulated anion channel subunit LRRC8E; LRRC8E; Leucine-rich repeat-containing protein 8E; anti-LRRC8E antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence
MGDIPDVKNDFAFMLHLIDQYDSLYSKRFAVFLSEVSESRLKQLNLNHEWTPEKLRQKLQRNAAGRLELALCMLPGLPDTVFELSEVESLRLEAICDITFPPGLSQLVHLQELSLLHSPARLPFSLQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCR
Sequence Length
796
Applicable Applications for anti-LRRC8E antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human volume-regulated anion channel subunit LRRC8E protein, corresponding to amino acids 353-630(Uniprot:Q6NSJ5-1)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-133764
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohistochemisry)
(Immunofluorescent analysis of HepG2 cells using AAA119674 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
IHC (Immunohistochemisry)
(Immunofluorescent analysis of HepG2 cells using AAA119674 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human lung tissue using AAA119674 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human lung tissue using AAA119674 at dilution of 1:100)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human gastric cancer using AAA119674 at dilution of 1:100)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human gastric cancer using AAA119674 at dilution of 1:100)
Related Product Information for anti-LRRC8E antibody
Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8E constitutes a pore-forming subunit or whether it is closely associated with the pore (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
90,247 Da
NCBI Official Full Name
volume-regulated anion channel subunit LRRC8E isoform 1
NCBI Official Synonym Full Names
leucine-rich repeat containing 8 family member E
NCBI Official Symbol
LRRC8E
NCBI Protein Information
volume-regulated anion channel subunit LRRC8E
UniProt Protein Name
Volume-regulated anion channel subunit LRRC8E
UniProt Gene Name
LRRC8E
UniProt Entry Name
LRC8E_HUMAN
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Product Notes
The LRRC8E lrrc8e (Catalog #AAA119674) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LRRC8E Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LRRC8E can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the LRRC8E lrrc8e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGDIPDVKND FAFMLHLIDQ YDSLYSKRFA VFLSEVSESR LKQLNLNHEW TPEKLRQKLQ RNAAGRLELA LCMLPGLPDT VFELSEVESL RLEAICDITF PPGLSQLVHL QELSLLHSPA RLPFSLQVFL RDHLKVMRVK CEELREVPLW VFGLRGLEEL HLEGLFPQEL ARAATLESLR ELKQLKVLSL RSNAGKVPAS VTDVAGHLQR LSLHNDGARL VALNSLKKLA ALRELELVAC GLERIPHAVF SLGALQELDL KDNHLRSIEE ILSFQHCR. It is sometimes possible for the material contained within the vial of "LRRC8E, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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