Rabbit LSP1 Polyclonal Antibody | anti-LSP1 antibody
LSP1 Rabbit anti-Human Polyclonal Antibody
Gene Names
LSP1; WP34; pp52
Reactivity
Mouse, Rat, Human
Applications
Western Blot, Immunohistochemistry
Purity
This antibody is purified by immunogen affinity chromatography
Synonyms
LSP1, Antibody; LSP1 Rabbit anti-Human Polyclonal Antibody; PathPlus LSP1 Antibody; LSP1; 47 kDa actin-binding protein; 47 kDa actin binding protein; 52 kDa phosphoprotein; Leukocyte-specific protein 1; Lymphocyte-specific protein 1; Pp52; WP34; anti-LSP1 antibody
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of LSP1 protein.
Purity/Purification
This antibody is purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-LSP1 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Target
Human LSP1
Immunogen
Recombinant full length protein of human LSP1
Conjugation
Unconjugated
Preparation and Storage
Upon delivery, aliquot and store at -20 degree C for 1 year. Avoid freeze/thaw cycles.
Related Product Information for anti-LSP1 antibody
LSP1 antibody is an unconjugated rabbit polyclonal antibody to LSP1 from human. It is reactive with human, mouse and rat. Validated for IHC and WB.
LSP1 is an intracellular F-actin binding protein expressed in lymphocytes, neutrophils, macrophages, and endothelium. It regulates neutrophil motility, adhesion to fibrinogen matrix proteins, transendothelial migration, and actomyosin contractility in macrophages. Some inherited polymorphisms in LSP1 are associated with increased risk for breast cancer. In immunohistochemistry, LSP1 has membranous and cytoplasmic positivity in immune cells.
LSP1 is an intracellular F-actin binding protein expressed in lymphocytes, neutrophils, macrophages, and endothelium. It regulates neutrophil motility, adhesion to fibrinogen matrix proteins, transendothelial migration, and actomyosin contractility in macrophages. Some inherited polymorphisms in LSP1 are associated with increased risk for breast cancer. In immunohistochemistry, LSP1 has membranous and cytoplasmic positivity in immune cells.
References
The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; Int J Clin Exp Pathol. 2015; 8(5): 5798 -5802, PMID: 26191300; Nat Commun 9, 515 (2018), DOI:10.1038/s41467-018-02904-x
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,389 Da
NCBI Official Full Name
lymphocyte-specific protein 1 isoform 1
NCBI Official Synonym Full Names
lymphocyte-specific protein 1
NCBI Official Symbol
LSP1
NCBI Official Synonym Symbols
WP34; pp52
NCBI Protein Information
lymphocyte-specific protein 1; 52 kDa phosphoprotein; 47 kDa actin binding protein; 47 kDa actin-binding protein; leukocyte-specific protein 1; lymphocyte-specific antigen WP34; leufactin (leukocyte F-actin binding protein); F-actin binding and cytoskelet
UniProt Protein Name
Lymphocyte-specific protein 1
UniProt Gene Name
LSP1
UniProt Synonym Gene Names
WP34; pp52
UniProt Entry Name
LSP1_HUMAN
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Product Notes
The LSP1 lsp1 (Catalog #AAA163343) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LSP1 Rabbit anti-Human Polyclonal Antibody reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's LSP1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the LSP1 lsp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LSP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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